Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Editorial
. 2018 Nov;30(11):2648.
doi: 10.1105/tpc.18.00810. Epub 2018 Oct 29.

Active Support: GHR1 Is a Pseudokinase That Acts as a Scaffolding Component

Estee E Tee  1
Affiliations
Editorial

Active Support: GHR1 Is a Pseudokinase That Acts as a Scaffolding Component

Estee E Tee. Plant Cell. 2018 Nov.
No abstract available

PubMed Disclaimer

Figures

None
Structure of the GHR1 Protein With Predicted Functional Domains. Mutant alleles identified from two independent forward-genetic ozone sensitivity screens allowed analysis of how the protein domains contribute to GHR1 function. ghr1-17 resulted in a truncated protein lacking most of the kinase domain. ghr1-7 and ghr1-8 mutant alleles caused nonsynonymous mutations of key residues required for SLAC1 activation (Adapted from Sierla et al. [2018], Figure 6).
See this image and copyright information in PMC

Comment on

  • The Receptor-like Pseudokinase GHR1 Is Required for Stomatal Closure.
    Sierla M, Hõrak H, Overmyer K, Waszczak C, Yarmolinsky D, Maierhofer T, Vainonen JP, Salojärvi J, Denessiouk K, Laanemets K, Tõldsepp K, Vahisalu T, Gauthier A, Puukko T, Paulin L, Auvinen P, Geiger D, Hedrich R, Kollist H, Kangasjärvi J. Sierla M, et al. Plant Cell. 2018 Nov;30(11):2813-2837. doi: 10.1105/tpc.18.00441. Epub 2018 Oct 25. Plant Cell. 2018. PMID: 30361234 Free PMC article.

References

    1. Hua D., Wang C., He J., Liao H., Duan Y., Zhu Z., Guo Y., Chen Z., Gong Z. (2012). A plasma membrane receptor kinase, GHR1, mediates abscisic acid- and hydrogen peroxide-regulated stomatal movement in Arabidopsis. Plant Cell 24: 2546–2561. - PMC - PubMed
    1. Scherzer S., Maierhofer T., Al-Rasheid K.A., Geiger D., Hedrich R. (2012). Multiple calcium-dependent kinases modulate ABA-activated guard cell anion channels. Mol. Plant 5: 1409–1412. - PubMed
    1. Sierla M., et al. (2018). The receptor-like pseudokinase GHR1 is required for stomatal closure. Plant Cell 30: 2813-2837. - PMC - PubMed

Substances

LinkOut - more resources