Following hearts, one cell at a time: recent applications of single-cell RNA sequencing to the understanding of heart disease
- PMID: 30375391
- PMCID: PMC6207674
- DOI: 10.1038/s41467-018-06894-8
Following hearts, one cell at a time: recent applications of single-cell RNA sequencing to the understanding of heart disease
Abstract
The mammalian heart contains heterogeneous cell types contributing to pathological changes in cardiac disease. In this Comment, we explore how single-cell transcriptomic approaches are unveiling intricate cellular mechanisms and gene co-expression networks that regulate the workings, and failings, of the heart.
Conflict of interest statement
The authors declare no competing interests.
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