Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Randomized Controlled Trial
. 2019 Feb;28(2):178-184.
doi: 10.1089/jwh.2017.6788. Epub 2018 Oct 30.

Dietary Quality and Glycemic Control Among Women with Gestational Diabetes Mellitus

Affiliations
Randomized Controlled Trial

Dietary Quality and Glycemic Control Among Women with Gestational Diabetes Mellitus

Meghana D Gadgil et al. J Womens Health (Larchmt). 2019 Feb.

Abstract

Background/objective: Poor dietary quality, measured by the Healthy Eating Index 2010 (HEI-2010), is associated with risk of gestational diabetes mellitus (GDM) and type 2 diabetes. The aim was to investigate the association between dietary quality and glycemic control in women with GDM.

Materials and methods: The study included 1220 women with GDM. Dietary quality was calculated by HEI-2010 score from a Food Frequency Questionnaire administered shortly after GDM diagnosis; higher scores indicate higher dietary quality. Subsequent glycemic control was defined as ≥80% of all capillary glucose measurements meeting recommended clinical targets below 95 mg/dL for fasting, and below 140 mg/dL 1-hour glucose after meals.

Results: As compared with Quartile 1 of HEI-2010 score, Quartiles 2, 3, and 4 showed increased adjusted odds of overall optimal glycemic control (odds ratio [95% confidence interval] 1.90 [1.34-2.70], 1.77 [1.25-2.52], and 1.55 [1.09-2.20], respectively). Increased odds of glycemic control were observed in Quartiles 2, 3, and 4 as compared with Quartile 1 of HEI-2010 score for 1-hour postbreakfast and 1-hour postdinner. Mean capillary glucose was lower in Quartiles 2, 3, and 4 of HEI-2010 score when compared with Quartile 1 for 1-hour postdinner (p = 0.03).

Conclusions: Clinicians should be aware that even a small improvement in diet quality may be beneficial for the achievement of improved glycemic control in women with GDM.

Trial registration: Clinical Trials.gov number, NCT01344278.

Keywords: diet; gestational diabetes; glycemic control; nutrition; pregnancy.

PubMed Disclaimer

Conflict of interest statement

No competing financial interests exist.

Figures

<b>FIG. 1.</b>
FIG. 1.
This flowchart represents the study cohort assembly. FFQ, Food Frequency Questionnaire at baseline.

References

    1. Ferrara A. Increasing prevalence of gestational diabetes mellitus: A public health perspective. Diabetes Care 2007;30(Suppl 2):141. - PubMed
    1. Landon MB, Spong CY, Thom E, et al. . A multicenter, randomized trial of treatment for mild gestational diabetes. N Engl J Med 2009;361:1339–1348 - PMC - PubMed
    1. American Diabetes Association. 12. Management of diabetes in pregnancy. Diabetes Care 2015;39(Suppl 1):S98 - PubMed
    1. Metzger BE, Buchanan TA, Coustan DR, et al. . Summary and recommendations of the Fifth International Workshop-Conference on Gestational Diabetes Mellitus. Diabetes Care 2007;30(Suppl 2):251 - PubMed
    1. Reader DM. Medical nutrition therapy and lifestyle interventions. Diabetes Care 2007;30(Suppl 2):188 - PubMed

Publication types

Associated data