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. 2018 Oct 30;7(1):173.
doi: 10.1038/s41426-018-0171-5.

A novel human coronavirus OC43 genotype detected in mainland China

Yun Zhu  1 , Changchong Li  2 , Li Chen  1 , Baoping Xu  3 , Yunlian Zhou  4 , Ling Cao  5 , Yunxiao Shang  6 , Zhou Fu  7 , Aihuan Chen  8 , Li Deng  9 , Yixiao Bao  10 , Yun Sun  11 , Limin Ning  12 , Chunyan Liu  1 , Ju Yin  3 , Zhengde Xie  13 , Kunling Shen  14
Affiliations

A novel human coronavirus OC43 genotype detected in mainland China

Yun Zhu et al. Emerg Microbes Infect. .
No abstract available

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Conflict of interest statement

The authors declare that they have no conflict of interest.

Figures

Fig. 1
Fig. 1. Genetic analysis of the HCoV-OC43 strains based on the whole-genome sequences.
a Phylogenetic tree of the HCoV-OC43 strains based on whole-genome sequences. The tree was constructed by using the maximum likelihood (ML) method with the best-fit general time reversible model with gamma-distributed rate variation across sites and 1000 bootstrap replicates implemented in MEGA 5.03. Bootstrap values over 70% are shown in the nodes. b Estimation of pairwise genetic distances between genotype H and genotypes A–G of HCoV-OC43 strains based on the whole-genome sequences
See this image and copyright information in PMC

References

    1. Masters, P. S. & Perlman, S. in Fields virology 6th edn, Vol. 1 (eds Knipe & Howley: Wolters Kluwer, Lippincott Williams & Wilkins) Ch. 28 (Philadelphia, 2013).
    1. Morfopoulou S, et al. Human coronavirus OC43 associated with fatal encephalitis. N. Engl. J. Med. 2016;375:497–498. doi: 10.1056/NEJMc1509458. - DOI - PubMed
    1. St-Jean JR, et al. Human respiratory coronavirus OC43: genetic stability and neuroinvasion. J. Virol. 2004;78:8824–8834. doi: 10.1128/JVI.78.16.8824-8834.2004. - DOI - PMC - PubMed
    1. Coleman CM, Frieman MB. Coronaviruses: important emerging human pathogens. J. Virol. 2014;88:5209–5212. doi: 10.1128/JVI.03488-13. - DOI - PMC - PubMed
    1. Woo PC, et al. Discovery of seven novel Mammalian and avian coronaviruses in the genus deltacoronavirus supports bat coronaviruses as the gene source of alphacoronavirus and betacoronavirus and avian coronaviruses as the gene source of gammacoronavirus and deltacoronavirus. J. Virol. 2012;86:3995–4008. doi: 10.1128/JVI.06540-11. - DOI - PMC - PubMed