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. 2019:1882:1-8.
doi: 10.1007/978-1-4939-8879-2_1.

Subtyping of IPMN

Toru Furukawa  1
Affiliations

Subtyping of IPMN

Toru Furukawa. Methods Mol Biol. 2019.

Abstract

Intraductal papillary mucinous neoplasms (IPMNs) characteristically consist of mucin-filled dilated ducts lined with neoplastic cells forming papillae with a diverse range of morphologies and varying grades of atypia. Based on morphological characteristics and immunohistochemical reaction against mucin proteins, IPMNs are classified into four distinct subtypes: gastric, intestinal, pancreatobiliary, and oncocytic. In this chapter, histomorphological criteria and techniques of immunohistochemical staining and its evaluation for subtyping IPMNs are described.

Keywords: Gastric; Intestinal; MUC1; MUC2; MUC5AC; MUC6; Oncocytic; Pancreatobiliary.

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