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. 2018 Oct 29;113(11):e170538.
doi: 10.1590/0074-02760170538.

Potential role of dengue virus, chikungunya virus and Zika virus in neurological diseases

Marcelo Adriano da Cunha E Silva Vieira  1   2   3 , Carlos Henrique Nery Costa  4 , Alexandre da Costa Linhares  5 , Amariles de Sousa Borba  2 , Daniele Freitas Henriques  6 , Eliana Vieira Pinto da Silva  6 , Fernando Neto Tavares  5 , Francisca Miriane de Araújo Batista  7 , Herlon Clístenes Lima Guimarães  7 , Lívia Carício Martins  6 , Talita Antônia Furtado Monteiro  3   5 , Ana Cecília Ribeiro Cruz  6 , Raimunda do Socorro da Silva Azevedo  6 , Pedro Fernando da Costa Vasconcelos  6
Affiliations

Potential role of dengue virus, chikungunya virus and Zika virus in neurological diseases

Marcelo Adriano da Cunha E Silva Vieira et al. Mem Inst Oswaldo Cruz. .

Abstract

This study showed that laboratory markers of recent infection by dengue, Zika or chikungunya arboviruses were detected in the biological samples of approximately one-third of patients with encephalitis, myelitis, encephalomyelitis or Guillain-Barré syndrome, in a surveillance programme in Piauí state, Brazil, between 2015-2016. Fever and myalgia had been associated with these cases. Since in non-tropical countries most infections or parainfectious diseases associated with the nervous system are attributed to herpesviruses, enteroviruses, and Campylobacter jejuni, the present findings indicate that in tropical countries, arboviruses may now play a more important role and reinforce the need for their surveillance and systematic investigation in the tropics.

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