Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2019 Jan;33(1):87-96.
doi: 10.1038/s41433-018-0244-7. Epub 2018 Nov 1.

Retinoblastoma in Asia

Affiliations
Review

Retinoblastoma in Asia

Mukesh Jain et al. Eye (Lond). 2019 Jan.

Abstract

Asia-Pacific region bears a significant global burden of retinoblastoma (RB), therefore understanding RB in Asia-Pacific region is important. Based on the year 2013 population estimates, 43% (3452 of 8099 children) of the global burden of RB lives in 6 countries of Asia-Pacific region: 1486 children in India, 1103 children in China, 277 children in Indonesia, 260 children in Pakistan, 184 children in Bangladesh, 142 children in Philippines. There exists a wide disparity, technological and socio-economical, within countries in this region resulting in a varied pattern of clinical presentation and survival varies. Challenges in developing nations are not just technological, but also social. Opportunities emerge for research to study and understand the socio-economical aspects of the disease to develop interventions that are relevant culturally and feasible economically. Possible steps include disease education and counselling, universal screening, highly subsidized/free of cost treatment for low socioeconomic strata, raising funds through the government and non-governmental organizations, sensitization and training of man-power in screening, diagnosis and treatment, and developing new specialized centers with tele-ophthalmology services.

摘要: 亚太地区是全球主要的视网膜母细胞瘤 (RB) 患病地区, 因此了解亚太地区RB的患病情况具有重要意义。根据2013年人口估计, 全球患RB儿童中的43%(8099名儿童中的3452名)生活在亚太地区的6个国家:印度1486名儿童、中国1103名儿童、印度尼西亚277名儿童、巴基斯坦260名儿童、孟加拉国184名儿童、菲律宾142名儿童。各国在技术和社会经济方面存在着巨大差异, 导致了临床表现和生存数量的不同。发展中国家面临的挑战不仅是技术方面的, 还有社会方面的。学习理解该疾病的社会经济方面的特点以制定与文化相关和经济可行性的干预措施很重要。可能采取的措施包括疾病的教育咨询、普遍筛查、对社会经济地位低的人群给予高补贴/免费治疗、通过政府和非政府组织筹集资金、提高筛查及诊断和治疗方面的人才的认识和培训, 以及发展具有远程眼科服务的新型专业中心。.

PubMed Disclaimer

Conflict of interest statement

The authors declare that they have no conflict of interest.

References

    1. Kivelä T. The epidemiological challenge of the most frequent eye cancer: retinoblastoma, an issue of birth and death. Br J Ophthalmol. 2009;93:1129–31. - PubMed
    1. Dimaras H, Kimani K, Dimba EA, Gronsdahl P, White A, Chan HS, et al. Retinoblastoma. Lancet. 2012;379:1436–46. - PubMed
    1. Kivelä T. 200 years of success initiated by James Wardrop’s 1809 monograph on retinoblastoma. Actaophthalmologica. 2009;8:810–2. - PubMed
    1. Abramson DH. Retinoblastoma in the 20th century: past success and future challenges the Weisenfeld lecture. Invest Ophthalmol & Vis Sci. 2005;46:2684–91. - PubMed
    1. Abramson DH, Beaverson K, Sangani P, Vora RA, Lee TC, Hochberg HM, et al. Screening for retinoblastoma: presenting signs as prognosticators of patient and ocular survival. Pediatrics. 2003;112:1248–55. - PubMed