Corrigendum: The NaV1.7 Channel Subtype as an Antinociceptive Target for Spider Toxins in Adult Dorsal Root Ganglia Neurons

Abstract

[This corrects the article DOI: 10.3389/fphar.2018.01000.].

Keywords: NaV1.7 channel subtype; dorsal root ganglia neurons; electrophysiology; pain; spider toxins; voltage-gated sodium channels.

Figure 1

Cellular elements involved in pain transmission from the peripheral to the central nervous system (CNS). (Box 1) The pain (thermal, high pressure, mechanical, chemical) information is first detected by the receptors located at the level of free nerve endings of primary sensory neuron (PSN) fibers. (Box 2) Then, it is conveyed by the dendrites of these neurons, components of dorsal root ganglia (DRG), to the dorsal horn of spinal cord where it is transmitted to the dendrites of secondary sensory neurons (SSNs). (Box 3) Finally, it is brought to the hypothalamus via the tertiary sensory neurons (TSNs) whose cell bodies constitute, in part, the brain cortex.