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. 2018 Nov 2;13(11):e0206650.
doi: 10.1371/journal.pone.0206650. eCollection 2018.

Antenatal depressive symptoms and adverse birth outcomes in Hanoi, Vietnam

Toan Van Ngo  1 , Tine Gammeltoft  2 , Hanh Thuy Thi Nguyen  1 , Dan W Meyrowitsch  3 , Vibeke Rasch  4   5
Affiliations

Antenatal depressive symptoms and adverse birth outcomes in Hanoi, Vietnam

Toan Van Ngo et al. PLoS One. .

Abstract

Background: Antenatal depression is a significant health problem in low and middle- income countries. Although the condition is associated with severe adverse consequences for the mother and newborn, it remains a neglected problem. The purpose of this study was to describe the association between antenatal depressive symptoms and preterm birth (PTB), low birth weight (LBW), and small for gestation age (SGA).

Methods: The study was conducted in Dong Anh District, Hanoi, Vietnam, among pregnant women of less than 24 weeks of gestation. Information on socioeconomic characteristics and reproductive history was collected at enrollment and ADS and experiences of intimate partner violence were assessed at week 32. Birth outcomes were determined at delivery. Bivariate and logistic regression analyses were applied to assess the associations between ADS and PTB, LBW, and SGA.

Results: ADS was significantly associated with an increased risk of PTB (crude OR = 2.4; 95%; CI: 1.01-5.4 and adjusted OR = 2.4; 95% CI: 1.1-5.2, respectively) and a significantly increased risk for giving birth to an LBW infant (crude OR = 3.1; 95% CI: 1.4-7.0 and adjusted OR = 3.5; 95% CI: 1.6-7.6, respectively). In contrast, ADS was not statistically associated with small for gestation age.

Conclusion: ADS is associated with an increased risk of PTB and LBW but not associated with SGA.

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Conflict of interest statement

The authors have declared that no competing interests exist.

Figures

Fig 1
Fig 1. Recruitment process.
See this image and copyright information in PMC

References

    1. March of Dimes P, Save The Children, WHO (2012) Born Too Soon: The Global Action Report on Preterm Birth.
    1. Liu C, Cnattingius S, Bergström M, Östberg V, Hjern A (2016) Prenatal parental depression and preterm birth: a national cohort study. Bjog 123: 1973–1982. 10.1111/1471-0528.13891 - DOI - PMC - PubMed
    1. Mochache K, Mathai M, Gachuno O, Vander Stoep A, Kumar M (2018) Depression during pregnancy and preterm delivery: a prospective cohort study among women attending antenatal clinic at Pumwani Maternity Hospital. Ann Gen Psychiatry 17: 31 10.1186/s12991-018-0202-6 - DOI - PMC - PubMed
    1. Rahman A, Bunn J, Lovel H, Creed F (2007) Association between antenatal depression and low birthweight in a developing country. Acta Psychiatr Scand 115: 481–486. 10.1111/j.1600-0447.2006.00950.x - DOI - PMC - PubMed
    1. Ecklund-Flores L, Myers MM, Monk C, Perez A, Odendaal HJ, Fifer WP (2017) Maternal depression during pregnancy is associated with increased birth weight in term infants. Dev Psychobiol 59: 314–323. 10.1002/dev.21496 - DOI - PMC - PubMed

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