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Comment
. 2018 Nov 1;72(3):402-403.
doi: 10.1016/j.molcel.2018.10.027.

Evolution at the Cutting Edge: CRISPR-Mediated Directed Evolution

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Evolution at the Cutting Edge: CRISPR-Mediated Directed Evolution

Timothy R Abbott et al. Mol Cell. .
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Abstract

In a recent issue of Nature, Halperin et al. (2018) develop a new technology to continuously diversify specific genomic loci by combining CRISPR-Cas9 with error-prone DNA polymerases.

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