Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Randomized Controlled Trial
. 2019 Mar;102(3):528-535.
doi: 10.1016/j.pec.2018.10.009. Epub 2018 Oct 12.

Biomarker feedback intervention for smoking cessation among Alaska Native pregnant women: Randomized pilot study

Christi A Patten  1 , Kathryn R Koller  2 , Christie A Flanagan  2 , Vanessa Y Hiratsuka  3 , Christine A Hughes  4 , Abbie W Wolfe  2 , Paul A Decker  5 , Kristin Fruth  5 , Tabetha A Brockman  4 , Molly Korpela  3 , Diana Gamez  3 , Carrie Bronars  4 , Neil J Murphy  3 , Dorothy Hatsukami  6 , Neal L Benowitz  7 , Timothy K Thomas  2
Affiliations
Randomized Controlled Trial

Biomarker feedback intervention for smoking cessation among Alaska Native pregnant women: Randomized pilot study

Christi A Patten et al. Patient Educ Couns. 2019 Mar.

Abstract

Objective: There is some evidence for biomarker feedback when combined with cessation counseling for reducing smoking in pregnancy. This randomized controlled pilot study evaluated feasibility and potential efficacy of a social-cognitive theory (SCT)-based biomarker feedback intervention among pregnant Alaska Native (AN) smokers.

Methods: Participants were randomly assigned to receive three study calls (10-20 min each): (1) biomarker feedback intervention (n = 30) including personalized cotinine results and feedback on their baby's likely exposure to carcinogen metabolite NNAL, or (2) contact control usual care condition based on the 5As (n = 30). Assessments were conducted at baseline, post-treatment, and delivery.

Results: High rates of treatment compliance, study retention, and treatment acceptability were observed in both groups. 7-day point prevalence smoking abstinence rates at delivery verified with urinary cotinine were the same in both study groups (20% intent-to-treat analysis, 26% per-protocol). SCT-based measures did not change differentially from baseline by study group.

Conclusion: This trial supports the feasibility and acceptability of providing biomarker feedback within the clinical care delivery system, but the intervention did not promote increased smoking cessation during pregnancy compared to usual care.

Practice implications: Efforts are needed to promote the usual care and to develop alternative biomarker feedback messaging for pregnant AN women.

Keywords: Alaska Native; Biomarker feedback; Cigarette smoking; Intervention; Pregnancy; Smoking cessation.

PubMed Disclaimer

Conflict of interest statement

Declaration of interests

NLB is a consultant to several pharmaceutical companies that market medications to aid smoking cessation and has served as a paid expert witness in litigation against tobacco companies. The other authors have no conflicts to disclose.

Figures

Fig. 1:
Fig. 1:
Participant flow.
See this image and copyright information in PMC

Similar articles

See all similar articles

Cited by

See all "Cited by" articles

References

    1. Bauld L, Oncken C, Smoking in pregnancy: an ongoing challenge, Nicotine Tob Res. 19 (2017) 495–496. doi:10.1093/ntr/ntx034. - DOI - PubMed
    1. Curtin SC, Matthews TJ, Smoking prevalence and cessation before and during pregnancy: data from the birth certificate, 2014, Natl Vital Stat Rep. 65 (2016) 1–14. - PubMed
    1. U.S. Department of Health and Human Services, The Health Consequences of Smoking: 50 years of progress A Report of the Surgeon General, U.S. Department of Health and Human Services, Centers for Disease Control and Prevention, National Center for Chronic Disease Prevention and Health Promotion, Office on Smoking and Health, Atlanta, GA, 2014.
    1. Tong VT, Dietz PM, Morrow B, D’Angelo DV, Farr SL, Rockhill KM, England LJ, Centers for Disease Control and Prevention (CDC), Trends in smoking before, during, and after pregnancy--Pregnancy Risk Assessment Monitoring System, United States, 40 sites, 2000–2010, MMWR Surveill Summ. 62 (2013) 1–19. - PubMed
    1. Kurti AN, Redner R, Lopez AA, Keith DR, Villanti AC, Stanton CA, Gaalema DE, Bunn JY, Doogan NJ, Cepeda-Benito A, Roberts ME, Phillips J, Higgins ST, Tobacco and nicotine delivery product use in a national sample of pregnant women, Prev Med. 104 (2017) 50–56. doi:10.1016/j.ypmed.2017.07.030. - DOI - PMC - PubMed

Publication types

MeSH terms