Characterization of somatically acquired ecotropic and mink cell focus-forming viruses in lymphomas of AKXD recombinant inbred mice
- PMID: 3039180
- PMCID: PMC255826
- DOI: 10.1128/JVI.61.9.2929-2933.1987
Characterization of somatically acquired ecotropic and mink cell focus-forming viruses in lymphomas of AKXD recombinant inbred mice
Abstract
The DNA of lymphomas from 12 AKXD recombinant inbred mouse strains was analyzed to determine the presence of somatically acquired ecotropic and mink cell focus-forming proviruses. Mink cell focus-forming proviruses were associated primarily with T-cell lymphomas, whereas ecotropic proviruses were associated with lymphomas of B-cell and myeloid lineages. A model based on the results is proposed to explain the variation in lymphoma types observed in different AKXD strains.
Similar articles
-
Comparative molecular genetic analysis of lymphomas from six inbred mouse strains.J Virol. 1988 Mar;62(3):839-46. doi: 10.1128/JVI.62.3.839-846.1988. J Virol. 1988. PMID: 2828679 Free PMC article.
-
N-methyl-N-nitrosourea-induced T-lymphomas of AKR/J mice contain somatically acquired ecotropic-like murine leukemia proviruses.Virology. 1988 May;164(1):211-9. doi: 10.1016/0042-6822(88)90638-1. Virology. 1988. PMID: 2834870
-
Susceptibility of AKXD recombinant inbred mouse strains to lymphomas.J Virol. 1993 Apr;67(4):2083-90. doi: 10.1128/JVI.67.4.2083-2090.1993. J Virol. 1993. PMID: 8383230 Free PMC article.
-
Ecotropic and mink cell focus-forming murine leukemia viruses integrate in mouse T, B, and non-T/non-B cell lymphoma DNA.J Virol. 1986 Mar;57(3):1037-47. doi: 10.1128/JVI.57.3.1037-1047.1986. J Virol. 1986. PMID: 3005610 Free PMC article.
-
Ecotropic virus involvement in spontaneous B-cell lymphomas of CWD/LeAgl mice.Leuk Res. 1989;13(5):417-25. doi: 10.1016/0145-2126(89)90082-9. Leuk Res. 1989. PMID: 2545977
Cited by
-
Infection by mink cell focus-forming viruses confers interleukin 2 (IL-2) independence to an IL-2-dependent rat T-cell lymphoma line.Proc Natl Acad Sci U S A. 1991 Jun 1;88(11):4611-5. doi: 10.1073/pnas.88.11.4611. Proc Natl Acad Sci U S A. 1991. PMID: 2052545 Free PMC article.
-
Comparative molecular genetic analysis of lymphomas from six inbred mouse strains.J Virol. 1988 Mar;62(3):839-46. doi: 10.1128/JVI.62.3.839-846.1988. J Virol. 1988. PMID: 2828679 Free PMC article.
-
Irradiated Blm-deficient mice are a highly tumor prone model for analysis of a broad spectrum of hematologic malignancies.Leuk Res. 2010 Feb;34(2):210-20. doi: 10.1016/j.leukres.2009.06.007. Epub 2009 Aug 25. Leuk Res. 2010. PMID: 19709744 Free PMC article.
-
B-Cell lymphoma induction by akv murine leukemia viruses harboring one or both copies of the tandem repeat in the U3 enhancer.J Virol. 1998 Jul;72(7):5745-56. doi: 10.1128/JVI.72.7.5745-5756.1998. J Virol. 1998. PMID: 9621033 Free PMC article.
-
Nucleotide sequence and distinctive characteristics of the env gene of endogenous feline leukemia provirus.J Virol. 1989 May;63(5):2379-84. doi: 10.1128/JVI.63.5.2379-2384.1989. J Virol. 1989. PMID: 2539525 Free PMC article.
References
Publication types
MeSH terms
Substances
Grants and funding
LinkOut - more resources
Full Text Sources
Medical
Molecular Biology Databases