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. 1987 Sep;61(9):2929-33.
doi: 10.1128/JVI.61.9.2929-2933.1987.

Characterization of somatically acquired ecotropic and mink cell focus-forming viruses in lymphomas of AKXD recombinant inbred mice

M L Mucenski, B A Taylor, N G Copeland, N A Jenkins

Characterization of somatically acquired ecotropic and mink cell focus-forming viruses in lymphomas of AKXD recombinant inbred mice

M L Mucenski et al. J Virol. 1987 Sep.

Abstract

The DNA of lymphomas from 12 AKXD recombinant inbred mouse strains was analyzed to determine the presence of somatically acquired ecotropic and mink cell focus-forming proviruses. Mink cell focus-forming proviruses were associated primarily with T-cell lymphomas, whereas ecotropic proviruses were associated with lymphomas of B-cell and myeloid lineages. A model based on the results is proposed to explain the variation in lymphoma types observed in different AKXD strains.

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References

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    1. Nature. 1984 Mar 29-Apr 4;308(5958):467-70 - PubMed
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