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. 2018 Oct 23;98(39):3158-3161.
doi: 10.3760/cma.j.issn.0376-2491.2018.39.006.

[The diagnostic value of low dose of dual-source CT venography for deep venous thrombosis]

[Article in Chinese]

[The diagnostic value of low dose of dual-source CT venography for deep venous thrombosis]

[Article in Chinese]
Z Z Wu et al. Zhonghua Yi Xue Za Zhi. .

Abstract

Objective: To investigate the diagnostic value of low dose of dual-source CT venography examination for DVT (deep venous thrombosis). Methods: A total of 60 patients from Nanjing First Hospital with suspected DVT underwent indirect low dose CTV examination and treatment of DSA from January to December, 2017, and recording the radiation dose for CTV.DSA as the gold standard, calculate the sensitivity, specificity of CTV, kappa consistency test was used to exam the results of CTV and DSA.McNemar test was used to check statistical difference between two examinations. Results: A total of 60 patients, 780 blood vessels took CTV examinations, 326 were positive; 420 blood vessels took DSA examinations, 332 were positive.DSA as the gold standard, the sensitivity, specificity, of DVT detection by CTV were 96.2% and 92.6%, kappa=0.860, P<0.05, and the result of McNemar test was P=0.263. Conclusion: Low dose of dual-source indirect CTV examination for DVT can not only reduce radiation dose for the patients, but also has a high clinical value in the diagnosis of DVT.

目的: 探讨双源CT低剂量间接法下肢深静脉造影(CTV)诊断下肢深静脉血栓形成的价值。 方法: 2017年1至12月南京医科大学附属南京医院共60例疑诊下肢深静脉血栓的患者进行了间接法低剂量CT静脉造影检查及下肢静脉DSA诊治,记录CTV辐射剂量并由两名高年资医师对CTV及DSA的原始图像进行分析得出诊断结果,以DSA为金标准,计算CTV的灵敏度、特异度;使用kappa一致性检验分析CTV与DSA两种检查方法对DVT诊断结果的一致性。用配对χ(2)检验两种检查方法差异是否有统计学意义。 结果: 60例患者共780支血管接受CTV检查,其中326支血管有阳性发现,60例患者共420支血管均行单侧下肢静脉DSA诊疗,其中332支血管有阳性发现。以DSA检查结果为金标准,CTV的灵敏度为96.2%,特异度为92.6%。kappa=0.860,P<0.05;配对χ(2)检验,P=0.263。 结论: 双源CT低剂量间接法下肢深静脉造影不仅能大幅度降低患者的辐射剂量,并且对诊断下肢深静脉血栓有较高的临床应用价值。.

Keywords: Angiography, digital subtraction; Radiation dosage; Tomography, X-ray computed; Venous thrombosis.

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