Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2018 Aug 12;2018(3):24.
doi: 10.21542/gcsp.2018.24.

Risk stratification in childhood hypertrophic cardiomyopathy

Affiliations
Review

Risk stratification in childhood hypertrophic cardiomyopathy

Gabrielle Norrish et al. Glob Cardiol Sci Pract. .
No abstract available

PubMed Disclaimer

Figures

Figure 1.
Figure 1.. a) Hazard ratios for sudden cardiac death or cardiovascular death for previous adverse event.
The size of the square corresponds with the number of patients in the study. The bars represent the upper and lower 95% CI. Hazard ratios with CI >1 indicate a significant association with sudden cardiac death. b) Odds ratios for sudden cardiac death or cardiovascular death for previous adverse event. The size of the square corresponds with the number of patients in the study. The bars represent the upper and lower 95% CI. Odds ratios with CI >1 indicate a significant association with sudden cardiac death. Reproduced from Norrish et al.
Figure 2.
Figure 2.
a) Hazard ratios for sudden cardiac death or cardiovascular death for unexplained syncope. b) Odds ratio for sudden cardiac death or cardiovascular death for unexplained syncope. Reproduced from Norrish et al. .
Figure 3.
Figure 3.
a) Hazard ratios for sudden cardiac death or cardiovascular death for non-sustained VT. b) Odds ratio for sudden cardiac death or cardiovascular death for non-sustained VT. Reproduced from Norrish et al.
Figure 4.
Figure 4.
a) Hazard ratios for sudden cardiac death or cardiovascular death for extreme LVH. b) Odds ratio for sudden cardiac death or cardiovascular death for extreme LVH. Reproduced from Norrish et al.
Figure 5.
Figure 5.. European Society of Cardiology recommendations for implantation of cardioverter defibrillators in children.
*Major paediatric risk factors: Maximum left ventricular wall thickness ≥30mmor a Z-score ≥6, unexplained syncope, non-sustained ventricular tachycardia (≥3 consecutive ventricular beats at ≥120 BPM lasting, 30 seconds), family history of SCD (one or more first-degree relatives with SCD aged, 40 years with or without the diagnosis of HCM, or SCD in a first-degree relative at any age with an established diagnosis of HCM).

References

    1. Nugent AW, Daubeney PE, Chondros P, et al. The epidemiology of childhood cardiomyopathy in Australia. N Engl J Med. 2003;348(17):1639–1646. - PubMed
    1. Lipshultz SE, Sleeper LA, Towbin JA, et al. The incidence of pediatric cardiomyopathy in two regions of the United States. N Engl J Med. 2003;348(17):1647–1655. - PubMed
    1. Arola A, Jokinen E, Ruuskanen O, et al. Epidemiology of idiopathic cardiomyopathies in children and adolescents. A nationwide study in Finland. American journal of epidemiology. 1997;146(5):385–393. - PubMed
    1. Lipshultz SE, Orav EJ, Wilkinson JD, et al. Risk stratification at diagnosis for children with hypertrophic cardiomyopathy: an analysis of data from the Pediatric Cardiomyopathy Registry. Lancet (London, England) 2013;382(9908):1889–1897. - PMC - PubMed
    1. Colan SD, Lipshultz SE, Lowe AM, et al. Epidemiology and cause-specific outcome of hypertrophic cardiomyopathy in children: findings from the Pediatric Cardiomyopathy Registry. Circulation. 2007;115(6):773–781. - PubMed

LinkOut - more resources