Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2019 Jan 8;47(D1):D23-D28.
doi: 10.1093/nar/gky1069.

Database resources of the National Center for Biotechnology Information

Affiliations

Database resources of the National Center for Biotechnology Information

Eric W Sayers et al. Nucleic Acids Res. .

Abstract

The National Center for Biotechnology Information (NCBI) provides a large suite of online resources for biological information and data, including the GenBank® nucleic acid sequence database and the PubMed database of citations and abstracts published in life science journals. The Entrez system provides search and retrieval operations for most of these data from 38 distinct databases. The E-utilities serve as the programming interface for the Entrez system. Augmenting many of the web applications are custom implementations of the BLAST program optimized to search specialized data sets. New resources released in the past year include PubMed Labs and a new sequence database search. Resources that were updated in the past year include PubMed, PMC, Bookshelf, genome data viewer, Assembly, prokaryotic genomes, Genome, BioProject, dbSNP, dbVar, BLAST databases, igBLAST, iCn3D and PubChem. All of these resources can be accessed through the NCBI home page at www.ncbi.nlm.nih.gov.

PubMed Disclaimer

Figures

Figure 1.
Figure 1.
Annual growth rates of the number of records in each Entrez database as of 1 September 2018. Identical Protein Groups is not included since this database was released during the past year. Please see the text for a discussion of a change in scope for dbVar and SNP.

References

    1. Schuler G.D., Epstein J.A., Ohkawa H., Kans J.A.. Entrez: molecular biology database and retrieval system. Methods Enzymol. 1996; 266:141–162. - PubMed
    1. Benson D.A., Cavanaugh M., Clark K., Karsch-Mizrachi I., Ostell J., Pruitt K.D., Sayers E.W.. GenBank. Nucleic Acids Res. 2018; 46:D41–D47. - PMC - PubMed
    1. Silvester N., Alako B., Amid C., Cerdeno-Tarraga A., Clarke L., Cleland I., Harrison P.W., Jayathilaka S., Kay S., Keane T. et al. . The European Nucleotide Archive in 2017. Nucleic Acids Res. 2018; 46:D36–D40. - PMC - PubMed
    1. Kodama Y., Mashima J., Kosuge T., Kaminuma E., Ogasawara O., Okubo K., Nakamura Y., Takagi T.. DNA Data Bank of Japan: 30th anniversary. Nucleic Acids Res. 2018; 46:D30–D35. - PMC - PubMed
    1. Karsch-Mizrachi I., Takagi T., Cochrane G. International Nucleotide Sequence Database, C. . The international nucleotide sequence database collaboration. Nucleic Acids Res. 2018; 46:D48–D51. - PMC - PubMed

Publication types