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. 1996 Aug;7(8):2165-2168.
doi: 10.1016/0957-4166(96)00261-3.

ASYMMETRIC HETERO DIELS-ALDER REACTIONS OF DANISHEFSKY'S DIENE AND GLYOXYLATE ESTERS CATALYZED BY CHIRAL BISOXAZOLINE DERIVED CATALYSTS

Arun K Ghosh  1 , Packiarajan Mathivanan  1 , John Cappiello  1 , K Krishnan  1
Affiliations

ASYMMETRIC HETERO DIELS-ALDER REACTIONS OF DANISHEFSKY'S DIENE AND GLYOXYLATE ESTERS CATALYZED BY CHIRAL BISOXAZOLINE DERIVED CATALYSTS

Arun K Ghosh et al. Tetrahedron Asymmetry. 1996 Aug.

Abstract

Asymmetric hetero Diels-Alder reactions of Danishefsky's diene and glyoxylate esters catalyzed by bis(oxazoline)-metal complex afforded the corresponding aldol adduct which upon treatment with trifluoroacetic acid furnished the hetero Diels-Alder product in 72% enantiomeric excess and 70% isolated yield.

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Figures

Scheme 1
Scheme 1
None
See this image and copyright information in PMC

References

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