Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2018 Nov 6;17(Suppl 2):146.
doi: 10.1186/s12938-018-0576-3.

Retrieving hidden atrial repolarization waves from standard surface ECGs

Affiliations

Retrieving hidden atrial repolarization waves from standard surface ECGs

Wei-Hua Tang et al. Biomed Eng Online. .

Abstract

Background: This study estimates atrial repolarization activities (Ta waves), which are typically hidden most of the time from body surface electrocardiography when diagnosing cardiovascular diseases. The morphology of Ta waves has been proven to be an important marker for the early sign of inferior injury, such as acute atrial infarction, or arrhythmia, such as atrial fibrillation. However, Ta waves are usually unseen except during conduction system malfunction, such as long QT interval or atrioventricular block. Therefore, justifying heart diseases based on atrial repolarization becomes impossible in sinus rhythm.

Methods: We obtain TMPs in the atrial part of the myocardium which reflects the correct excitation sequence starting from the atrium to the end of the apex.

Results: The resulting TMP shows the hidden atrial part of ECG waves.

Conclusions: This extraction makes many diseases, such as acute atrial infarction or arrhythmia, become easily diagnosed.

Keywords: Atrial repolarization waves; Electrophysiology model; Kalman filter; Monte Carlo Markov chain; Reaction–diffusion system.

PubMed Disclaimer

Figures

Fig. 1
Fig. 1
Geometries of heart and torso
Fig. 2
Fig. 2
TMP and surface ECG
Fig. 3
Fig. 3
Results of 12-lead ECG with MCMC. Top: atrial part of TMP; 2nd: original ECG; 3rd: simulated ECG; bottom: atrial part of simulated ECG

References

    1. Ihara Z, van Oosterom A, Hoekema R. Atrial repolarization as observable during the PQ interval. J Electrocardiol. 2006;39(3):290–297. doi: 10.1016/j.jelectrocard.2005.12.001. - DOI - PubMed
    1. Holmqvist F, Carlson J, Platonov PG. Detailed ecg analysis of atrial repolarization in humans. Ann Noninvasive Electrocardiol. 2009;14(1):13–18. doi: 10.1111/j.1542-474X.2008.00268.x. - DOI - PMC - PubMed
    1. Stridh M, Sörnmo L. Spatiotemporal qrst cancellation techniques for analysis of atrial fibrillation. IEEE Trans Biomed Eng. 2001;48(1):105–111. doi: 10.1109/10.900266. - DOI - PubMed
    1. Rieta JJ, Castells F, Sánchez C, Zarzoso V, Millet J. Atrial activity extraction for atrial fibrillation analysis using blind source separation. IEEE Trans Biomed Eng. 2004;51(7):1176–1186. doi: 10.1109/TBME.2004.827272. - DOI - PubMed
    1. Lemay M, Vesin J-M, Van Oosterom A, Jacquemet V, Kappenberger L. Cancellation of ventricular activity in the ECG: evaluation of novel and existing methods. IEEE Trans Biomed Eng. 2007;54(3):542–546. doi: 10.1109/TBME.2006.888835. - DOI - PubMed

LinkOut - more resources