Clinical and microbiological effects of the supplementary use of an erythritol powder air-polishing device in non-surgical periodontal therapy: a randomized clinical trial

Abstract

Purpose: This study was undertaken to evaluate the clinical and microbiological effects of an erythritol powder air-polishing device (EPAP) as a supplement to scaling and root planing (SRP) therapy in patients with moderate chronic periodontitis.

Methods: Clinical and microbiological evaluations were performed at 21 sites treated with SRP (control) and 21 sites treated with SRP+EPAP (test). All examinations were performed before treatment, 1 month after treatment, and 3 months after treatment.

Results: There were no significant clinical differences between the test group and the control group. Microbiological analysis revealed that the relative expression level of Porphyromonas gingivalis was significantly lower in the test group than in the control group at 1 month after treatment. Clinical and microbiological results showed improvements at 1 month compared to baseline; in contrast, the results at 3 months after treatment were worse than those at 1 month after treatment.

Conclusions: In this study, both SRP and SRP+EPAP were clinically and microbiologically effective as non-surgical periodontal treatments. In particular, the SRP+EPAP group showed an antimicrobial effect on P. gingivalis, a keystone bacterium associated with the onset of chronic periodontitis, in a short-term period. Periodic periodontal therapy, at intervals of at least every 3 months, is important for sustaining the microbiological effects of this treatment.

Keywords: Clinical trial; Dental scaling; Erythritol; Periodontitis; Porphyromonas gingivalis; Root planing.

Figure 1. Total bacterial count at baseline, 1 month after treatment, and 3 months after treatment, compared between the test and control groups.

SRP: scaling and root planning, EPAP: erythritol powder air-polishing device, 1MC: 1-month check, 3MC: 3-month check. ^a)Statistically significant (P<0.05). Error bars indicate standard deviation.

Figure 2. Relative levels of A. actinomycetemcomitans, C. rectus, E. corrodens, F. nucleatum spp., P. gingivalis, P. intermedia, T. denticola, and T. forsythia between test and control groups at baseline, 1 month after treatment, and 3 months after treatment

SRP: scaling and root planning, EPAP: erythritol powder air-polishing device, 1MC: 1-month check, 3MC: 3-month check. ^a)Statistically significant (P<0.05). Error bars indicate standard deviation.