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Review
. 2018 Oct 23:8:473.
doi: 10.3389/fonc.2018.00473. eCollection 2018.

The Antitumor Activities of Marsdenia tenacissima

Xiang Wang  1   2 , Yuanliang Yan  1   2 , Xi Chen  1   2 , Shuangshuang Zeng  1   2 , Long Qian  1   2 , Xinxin Ren  3 , Jie Wei  1   2 , Xue Yang  1   2 , Yangying Zhou  4 , Zhicheng Gong  1   2 , Zhijie Xu  5
Affiliations
Review

The Antitumor Activities of Marsdenia tenacissima

Xiang Wang et al. Front Oncol. .

Abstract

Marsdenia tenacissima (MT), a traditional Chinese herbal medicine, has long been used for thousands of years to treat asthma, tracheitis, rheumatism, etc. An increasing number of recent studies have focused on the antitumor effects of MT. The effects of MT on cancer are the result of various activated signaling pathways and inhibiting factors and the high expression levels of regulatory proteins. MT can inhibit different cancer types including non-small cell lung cancer (NSCLC), malignant tumors, hepatic carcinoma, and so on. This article mainly focuses on the activities and mechanisms of MT. In addition, the efficacy and toxicity of MT are also discussed. Further studies of MT are required for improved medicinal utilization.

Keywords: Marsdenia tenacissima; antitumor activities; efficacy; malignant tumor; signaling pathways; toxicity.

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Figures

Figure 1
Figure 1
The substances associated with Marsdenia tenacissima. The main components of the Xiao-Ai-Ping (XAP) injection is Marsdenia tenacissima (MT).
Figure 2
Figure 2
The mechanisms and biological effects of Marsdenia tenacissima in cancer research.
See this image and copyright information in PMC

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