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. 2018 Nov 5;4(4):00051-2018.
doi: 10.1183/23120541.00051-2018. eCollection 2018 Oct.

Reflux in idiopathic pulmonary fibrosis: treatment informed by an integrated approach

Rhys Jones  1   2 , Amaran Krishnan  1   2 , Gemma L Zeybel  3 , Emily Dookun  3 , Jeffrey P Pearson  3 , A John Simpson  4 , S Michael Griffin  1 , Chris Ward  3   4   5 , Ian A Forrest  6   5
Affiliations

Reflux in idiopathic pulmonary fibrosis: treatment informed by an integrated approach

Rhys Jones et al. ERJ Open Res. .

Abstract

After MDT work-up and review, gastro-oesophageal reflux and pulmonary aspiration were found to be common in IPF patients; surgery was recommended in only 10% http://ow.ly/rO3T30lU17o.

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Conflict of interest statement

Conflict of interest: None declared.

Figures

FIGURE 1
FIGURE 1
a) Flowchart of study recruitment and participation; b) concentrations of pepsin measured in bronchoalveolar lavage fluid from healthy volunteer controls and idiopathic pulmonary fibrosis (IPF) study patients. Study patients with high DeMeester scores (pH assessment) or supranormal total reflux events (impedance assessment) are indicated as IPF+GOR (gastro-oesophageal reflux disease).
See this image and copyright information in PMC

References

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    1. Belafsky PC, Postma GN, Koufman JA. Validity and reliability of the reflux symptom index (RSI). J Voice 2002; 16: 274–277. - PubMed

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