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. 2018 Nov 7;100(3):511-513.
doi: 10.1016/j.neuron.2018.10.039.

Inflamed Astrocytes: A Path to Depression Led by Menin

Fernanda Neutzling Kaufmann  1 , Caroline Menard  2
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Inflamed Astrocytes: A Path to Depression Led by Menin

Fernanda Neutzling Kaufmann et al. Neuron. .
Free article

Abstract

Increasing evidence supports a role for inflammation in the development of mood disorders. In this issue of Neuron, Leng et al. (2018) show that reduction of menin expression in astrocytes of stress-related brain regions exacerbates neuroinflammation, promoting the establishment of depression-like behaviors in mice.

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