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Review
. 2018 Oct 16:11:267-270.
doi: 10.2147/IJNRD.S150539. eCollection 2018.

Renal transplantation in patients with Alport syndrome: patient selection, outcomes, and donor evaluation

Clifford E Kashtan  1
Affiliations
Review

Renal transplantation in patients with Alport syndrome: patient selection, outcomes, and donor evaluation

Clifford E Kashtan. Int J Nephrol Renovasc Dis. .

Abstract

Alport syndrome is an inherited disorder of basement membrane collagen IV that frequently results in end-stage renal disease. Patients with Alport syndrome who undergo renal transplantation have generally excellent outcomes. Posttransplant antiglomerular basement membrane nephritis is a rare complication of renal transplantation for Alport syndrome. Because Alport syndrome is a genetic disorder, potential related donors must be carefully evaluated in order to minimize harm.

Keywords: Alport syndrome; collagen IV; kidney transplantation; posttransplant anti-GBM nephritis.

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Conflict of interest statement

Disclosure The author reports no conflicts of interest in this work.

References

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