Intrusion of chlorinated hydrocarbons and their degradation products from contaminated soil. Measurement of indoor air quality and biomonitoring by analysis of end-exhaled air

Abstract

A historic soil contamination of chlorinated hydrocarbons from a former dry cleaning shop caused intrusion of vapors into a building currently used as bookshop. The aim of this study was to determine the indoor air quality and the uptake of soil contaminants and their degradation products. Samples of indoor air were collected over one week in the warm and one week in the cold season. Pre-shift and post-shift samples of end-exhaled air were collected from two employees. Chlorinated hydrocarbons were analyzed in indoor air and exhaled air samples using thermal desorption gas chromatography mass spectrometry (TD-GC-MS). Tetrachloroethylene (PER), and its degradation products trichloroethylene (TRI), 1,1-dichloroethylene (1,1-DCE), 1,2-cis-dichloroethylene (1,2-cis-DCE), 1,2-trans-dichloroethylene (1,2-trans-DCE), methylene chloride (MC) and vinyl chloride (VC) were determined in ambient air. PER was the prime contaminant with a week average (±sd) of 805.2 ± 598.6 μg/m³ in June 2016 and 1031 ± 499.3 μg/m³ in December 2017. MC, 1,2-cis-DCE and TRI were detected at concentrations below 2.3 μg/m³. 1,1-DCE and VC were not detected. In exhaled air PER, 1,1-DCE, and MC were detected in both June and December, whereas TRI, 1,2-cis-DCE and 1,2-trans-DCE were only detected on one or two days in the cold season. VC was not detected in exhaled air. For PER, the mean concentrations (±sd) in end-exhaled air increased from a five days (Mon-Fri) average pre-shift value of 22.2 ± 8.0 to a post-shift value of 52.6 ± 15.5 ng/L in the male shop owner (p < 0.01) and in the female cashier these values were 26.0 ± 3.6 and 63.6 ± 12.7 ng/L, respectively (p < 0.01). Intrusion of chlorinated soil contaminants resulted in contamination of indoor air above the current accepted indoor air level for PER of 250 μg/m³. For PER in end-exhaled air an accumulation over the workweek was not observed.

Keywords: Breath analysis; Human biological monitoring; Indoor air quality; Soil degradation; Tetrachloroethylene; Thermal desorption gas chromatography mass spectrometry.