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Review
. 2018 Dec;12(6):601-607.
doi: 10.1007/s11684-018-0648-6. Epub 2018 Nov 9.

Interplay between diet and genetic susceptibility in obesity and related traits

Tiange Wang  1 , Min Xu  1 , Yufang Bi  1 , Guang Ning  2
Affiliations
Review

Interplay between diet and genetic susceptibility in obesity and related traits

Tiange Wang et al. Front Med. 2018 Dec.

Abstract

The incidence of obesity has been rapidly increasing, and this condition has become a major public health threat. A substantial shift in environmental factors and lifestyle, such as unhealthy diet, is among the major driving forces of the global obesity pandemic. Longitudinal studies and randomized intervention trials have shown that genetic susceptibility to obesity may interact with dietary factors in relation to the body mass index and risk of obesity. This review summarized data from recent longitudinal studies and intervention studies on variations and diets and discussed the challenges and future prospects related to this area and public health implications.

Keywords: diet; genetic susceptibility; interaction; obesity.

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