Multidrug-resistant Clostridium difficile ribotypes 078 and 014/5-FLI01 in piglets from Costa Rica
- PMID: 30414919
- DOI: 10.1016/j.anaerobe.2018.11.004
Multidrug-resistant Clostridium difficile ribotypes 078 and 014/5-FLI01 in piglets from Costa Rica
Abstract
Though an overlap of Clostridium difficile PCR ribotypes (RT) in humans and animals has been noted -particularly in piglets-information regarding C. difficile isolates from swine is scarce in Latin America. A characterization of 10 C. difficile isolates obtained from this origin in Costa Rica revealed the presence of the RT078 (n = 4) and RT014/5-FLI01 (n = 6) ribotypes. Unlike two previous reports from the region, all isolates were multidrug resistant (MDR). According to a minimum spanning tree (MST) analysis, our RT078 isolates formed a clonal complex with some German RT078 isolates and the already noted overlap of RT078 strains in humans and animals. This unanticipated high level of genetic relatedness confirms the transcontinental spread and geographically unlimited clustering of RT078.
Keywords: Clostridium difficile; Multidrug resistance; RT014/5; RT078; Swine.
Copyright © 2018 Elsevier Ltd. All rights reserved.
Similar articles
-
The emergence of Clostridium difficile PCR ribotype 078 in piglets in the Czech Republic clusters with Clostridium difficile PCR ribotype 078 isolates from Germany, Japan and Taiwan.Int J Med Microbiol. 2018 Oct;308(7):770-775. doi: 10.1016/j.ijmm.2018.05.006. Epub 2018 May 29. Int J Med Microbiol. 2018. PMID: 29859665
-
Subtyping and antimicrobial susceptibility of Clostridium difficile PCR ribotype 078/126 isolates of human and animal origin.Vet Microbiol. 2017 Feb;199:15-22. doi: 10.1016/j.vetmic.2016.12.001. Epub 2016 Dec 5. Vet Microbiol. 2017. PMID: 28110780
-
Antibiotic resistance patterns and PCR-ribotyping of Clostridium difficile strains isolated from swine and dogs in Italy.Anaerobe. 2015 Feb;31:42-6. doi: 10.1016/j.anaerobe.2014.10.003. Epub 2014 Oct 12. Anaerobe. 2015. PMID: 25316022
-
Characterization of Clostridium difficile isolates collected during a phase 2b clinical study with SYN-004 (ribaxamase) for the prevention of C. difficile infection.Anaerobe. 2018 Oct;53:30-33. doi: 10.1016/j.anaerobe.2018.07.002. Epub 2018 Jul 5. Anaerobe. 2018. PMID: 29981838 Review.
-
Reprint of New opportunities for improved ribotyping of C. difficile clinical isolates by exploring their genomes.J Microbiol Methods. 2013 Dec;95(3):425-40. doi: 10.1016/j.mimet.2013.09.009. Epub 2013 Sep 16. J Microbiol Methods. 2013. PMID: 24050948 Review.
Cited by
-
Antimicrobial resistance and virulence profiles of Enterobacterales isolated from two-finger and three-finger sloths (Choloepus hoffmanni and Bradypus variegatus) of Costa Rica.PeerJ. 2022 Mar 11;10:e12911. doi: 10.7717/peerj.12911. eCollection 2022. PeerJ. 2022. PMID: 35295556 Free PMC article.
-
Antimicrobial resistance of Clostridioides difficile in veterinary medicine around the world: A scoping review of minimum inhibitory concentrations.One Health. 2024 Jul 20;19:100860. doi: 10.1016/j.onehlt.2024.100860. eCollection 2024 Dec. One Health. 2024. PMID: 39157654 Free PMC article.
-
Clostridium (Clostridioides) difficile in animals.J Vet Diagn Invest. 2020 Mar;32(2):213-221. doi: 10.1177/1040638719899081. Epub 2020 Jan 6. J Vet Diagn Invest. 2020. PMID: 31904312 Free PMC article. Review.
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
