Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Editorial
. 2018 Dec;15(12):963-965.
doi: 10.1080/14789450.2018.1547194. Epub 2018 Nov 15.

Small, but mighty? Searching for human microproteins and their potential for understanding health and disease

Annie Rathore  1 , Thomas F Martinez  1 , Qian Chu  1 , Alan Saghatelian  1
Affiliations
Editorial

Small, but mighty? Searching for human microproteins and their potential for understanding health and disease

Annie Rathore et al. Expert Rev Proteomics. 2018 Dec.
No abstract available

Keywords: Microproteins; small open reading frames (smORFs); small proteins.

PubMed Disclaimer

Conflict of interest statement

Declaration of Interest

The authors have no relevant affiliations or financial involvement with any organization or entity with a financial interest in or financial conflict with the subject matter or materials discussed in the manuscript. This includes employment, consultancies, honoraria, stock ownership or options, expert testimony, grants or patents received or pending, or royalties.

References

    1. Saghatelian A, Couso JP. Discovery and characterization of smORF-encoded bioactive polypeptides. Nat Chem Biol. 2015;11(12):909–916. - PMC - PubMed
    1. Burge CB, Karlin S. Finding the genes in genomic DNA. Curr Opin Struct Biol. 1998;8(3):346–54. - PubMed
    1. Basrai MA, Hieter P, Boeke JD. Small Open Reading Frames: Beautiful Needles in the Haystack. Genome Research. 1997;7(8):768–771. - PubMed
    1. Gray NK, Wickens M. Control of translation initiation in animals. Annu Rev Cell Dev Biol. 1998;14:399–458. - PubMed
    1. Hill JR, Morris DR. Cell-specific translational regulation of S-adenosylmethionine decarboxylase mRNA. Dependence on translation and coding capacity of the cis-acting upstream open reading frame. J Biol Chem. 1993;268(1):726–31. - PubMed

Publication types