Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2018 Oct 23:7:F1000 Faculty Rev-1684.
doi: 10.12688/f1000research.15393.1. eCollection 2018.

Recent advances in lung transplantation

Keith C Meyer  1
Affiliations
Review

Recent advances in lung transplantation

Keith C Meyer. F1000Res. .

Abstract

Lung transplantation can improve quality of life and prolong survival for individuals with end-stage lung disease, and many advances in the realms of both basic science and clinical research aspects of lung transplantation have emerged over the past few decades. However, many challenges must yet be overcome to increase post-transplant survival. These include successfully bridging patients to transplant, expanding the lung donor pool, inducing tolerance, and preventing a myriad of post-transplant complications that include primary graft dysfunction, forms of cellular and antibody-mediated rejection, chronic lung allograft dysfunction, and infections. The goal of this manuscript is to review salient recent and evolving advances in the field of lung transplantation.

Keywords: lung transplantation.

PubMed Disclaimer

Conflict of interest statement

No competing interests were disclosed.No competing interests were disclosed.No competing interests were disclosed.

References

    1. Weill D, Benden C, Corris PA, et al. : A consensus document for the selection of lung transplant candidates: 2014--an update from the Pulmonary Transplantation Council of the International Society for Heart and Lung Transplantation. J Heart Lung Transplant. 2015;34(1):1–15. 10.1016/j.healun.2014.06.014 - DOI - PubMed

    2. F1000 Recommendation

    1. Hook JL, Lederer DJ: Selecting lung transplant candidates: where do current guidelines fall short? Expert Rev Respir Med. 2012;6(1):51–61. 10.1586/ers.11.83 - DOI - PMC - PubMed

    2. F1000 Recommendation

    1. Wilson ME, Vakil AP, Kandel P, et al. : Pretransplant frailty is associated with decreased survival after lung transplantation. J Heart Lung Transplant. 2016;35(2):173–8. 10.1016/j.healun.2015.10.014 - DOI - PubMed
    1. Singer JP, Diamond JM, Anderson MR, et al. : Frailty phenotypes and mortality after lung transplantation: A prospective cohort study. Am J Transplant. 2018;18(8):1995–2004. 10.1111/ajt.14873 - DOI - PMC - PubMed

    2. F1000 Recommendation

    1. Eberlein M, Garrity ER, Orens JB: Lung allocation in the United States. Clin Chest Med. 2011;32(2):213–22. 10.1016/j.ccm.2011.02.004 - DOI - PubMed

    2. F1000 Recommendation

Publication types