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Review
. 2018 Nov 15;32(11):1477-1482.
doi: 10.7507/1002-1892.201804024.

[The application of urine derived stem cells in regeneration of musculoskeletal system]

[Article in Chinese]
Fei Xing  1 , Guoming Liu  1 , Xin Duan  1 , Zhou Xiang  2
Affiliations
Review

[The application of urine derived stem cells in regeneration of musculoskeletal system]

[Article in Chinese]
Fei Xing et al. Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi. .

Abstract
in English, Chinese

Objective: To review the application of urine derived stem cells (USCs) in regeneration of musculoskeletal system.

Methods: The original literature about USCs in the regeneration of musculoskeletal system was extensively reviewed and analyzed.

Results: The source of USCs is noninvasive and extensive. USCs express MSCs surface markers with stable proliferative and multi-directional differentiation capabilities, and are widely used in bone, skin, nerve, and other skeletal and muscle system regeneration fields and show a certain repair capacity.

Conclusion: USCs from non-invasive sources have a wide application prospect in the regeneration of musculoskeletal system, but the definite biological mechanism of its repair needs further study.

目的: 总结尿源性干细胞（urine derived stem cells，USCs）在骨骼肌肉系统再生领域的应用。.

方法: 查阅国内外近年来有关 USCs 在骨骼肌肉系统再生领域的相关文献，并进行综合分析。.

结果: USCs 取材无创，来源广泛，表达 MSCs 表面标记，具备稳定的增殖能力、多向分化潜能，被广泛应用于骨、皮肤、神经等骨骼肌肉系统的再生领域并展现了一定修复能力。.

结论: 无创来源 USCs 在骨骼肌肉系统再生领域具备良好的应用前景，但其修复的生物学机制尚需进一步研究。.

Keywords: Urine derived stem cells; bone repair; induced pluripotent stem cells; multi-differentiation; tissue engineering.

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References

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