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. 2020 Nov;26(11):682-687.
doi: 10.1097/SPV.0000000000000650.

Tamsulosin to Prevent Postoperative Urinary Retention After Female Pelvic Reconstructive Surgery

Graham C Chapman, David Sheyn, Andrey Petrikovets, Sangeeta T Mahajan, Sherif El-Nashar, Robert Pollard, Jeffrey M Mangel

Tamsulosin to Prevent Postoperative Urinary Retention After Female Pelvic Reconstructive Surgery

Graham C Chapman et al. Female Pelvic Med Reconstr Surg. 2020 Nov.

Abstract

Objective: This study aimed to determine the effect of tamsulosin on postoperative urinary retention in female patients after pelvic reconstructive surgery.

Methods: Data were obtained from a retrospective, matched cohort of female patients who were admitted after pelvic reconstructive surgery at a single academic institution. Patients who received tamsulosin were compared with those who did not at a 1:4 ratio, matched by surgical procedure. Patients were excluded if they were discharged on the day of surgery or if an intraoperative complication necessitated prolonged postoperative bladder drainage. Information on demographics, preoperative diagnoses, prolapse stage, preoperative voiding dysfunction, urodynamic findings, intraoperative details, postoperative complications, and voiding outcomes up to 6 weeks after surgery was gathered. The primary outcome was postoperative urinary retention, defined by failure of an active voiding trial.

Results: Patients underwent surgery between January 2016 and March 2018. We identified 35 patients who received tamsulosin and matched to 140 controls. Patients in the tamsulosin group were younger; groups were otherwise similar. Patients who received tamsulosin after surgery were less likely to develop postoperative urinary retention (2.9% vs 24.3%, P = 0.004). After controlling for confounders, multivariable logistic regression identified tamsulosin use as the only independent predictor of postoperative urinary retention with a significant protective effect (odds ratio, 0.09; 95% confidence interval, 0.01-0.67; P = 0.03).

Conclusions: Prophylactic tamsulosin use may be effective in preventing postoperative urinary retention in female patients undergoing pelvic reconstructive surgery.

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References

    1. Kowalik U, Plante MK. Urinary retention in surgical patients. Surg Clin North Am 2016;96(3):453–467.
    1. Ripperda CM, Kowalski JT, Chaudhry ZQ, et al. Predictors of early postoperative voiding dysfunction and other complications following a midurethral sling. Am J Obstet Gynecol 2016;215(5):656.e1–656.e6.
    1. Tunitsky-Bitton E, Murphy A, Barber MD, et al. Assessment of voiding after sling: a randomized trial of 2 methods of postoperative catheter management after midurethral sling surgery for stress urinary incontinence in women. Am J Obstet Gynecol 2015;212(5):597.e1–597.e9.
    1. Geynisman-Tan J, Dave-Heliker B, Bochenska K, et al. Duration of catheterization after retropubic midurethral sling. Female Pelvic Med Reconstr Surg 2018.
    1. Chong C, Kim HS, Suh DH, et al. Risk factors for urinary retention after vaginal hysterectomy for pelvic organ prolapse. Obstet Gynecol Sci 2016;59(2):137–143.

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