[Regulation of dentin remineralization progress by non-collagenous protein analogues]
- PMID: 30419663
- DOI: 10.3760/cma.j.issn.1002-0098.2018.11.014
[Regulation of dentin remineralization progress by non-collagenous protein analogues]
Abstract
The use of various biomimetic methods to achieve remineralization of demineralized dentin and the formation of an organic matrix-inorganic mineral complex with a certain mechanical strength has been a research hotspot in recent years in the field of stomatology, and it also provides a new idea for the restoration of dentin defect. Dentin biomineralization is a process that simulates the mineralization of biological tissue in nature in which the remineralization of dentin collagen is induced and regulated by organic macromolecules. This review summarizes the process of remineralization of decalcified dentin regulated by non-collagenous protein analogues in vitro.
利用各种仿生手段实现脱矿牙本质再矿化并形成具有一定力学强度的有机基质-无机矿物复合物,是近年牙齿修复领域的研究热点,也为修复牙本质缺损提供新思路。牙本质仿生矿化是模拟自然界中生物组织矿化的过程,在有机大分子的调控下,诱导牙本质胶原再矿化。本文就仿生分子体外调控脱矿牙本质再矿化过程的研究进展进行综述。.
Keywords: Amorphous calcium phosphate; Biomimetic materials; Dentin; Tooth remineralization.
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