Evolving Role of PET/CT-MRI in Assessing Muscle Disorders

Abstract

2-Deoxy-2-[¹⁸F]fluoroglucose (FDG) uptake in muscle is influenced by many normal physiologic processes and can also indicate pathology. Variability in physiologic uptake can be reduced with proper patient preparation, allowing for a better determination of abnormal activity. Although malignant diseases, such as rhabdomyosarcoma and skeletal muscle metastasis, are clear applications of FDG-PET/CT, there may be additional applications in infection and benign inflammatory disorders that warrant further research.

Keywords: FDG; Inflammatory muscle disorders; Muscle disorders; Musculoskeletal malignancies; PET/CT-MRI.