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Multicenter Study
. 2019 Jul;74(7):700-704.
doi: 10.1136/thoraxjnl-2018-212547. Epub 2018 Nov 12.

Second round results from the Manchester 'Lung Health Check' community-based targeted lung cancer screening pilot

Phil A Crosbie  1   2 , Haval Balata  1 , Matthew Evison  1 , Melanie Atack  3 , Val Bayliss-Brideaux  3 , Denis Colligan  3   4 , Rebecca Duerden  1 , Josephine Eaglesfield  3 , Timothy Edwards  1 , Peter Elton  5 , Julie Foster  6 , Melanie Greaves  1 , Graham Hayler  3 , Coral Higgins  4 , John Howells  7 , Klaus Irion  8 , Devinda Karunaratne  8 , Jodie Kelly  1 , Zoe King  3 , Judith Lyons  1 , Sarah Manson  1 , Stuart Mellor  9 , Donna Miller  10 , Amanda Myerscough  3 , Tom Newton  9 , Michelle O'Leary  11 , Rachel Pearson  3   4 , Julie Pickford  6 , Richard Sawyer  1 , Nick J Screaton  12 , Anna Sharman  1 , Maggi Simmons  3 , Elaine Smith  1 , Ben Taylor  13 , Sarah Taylor  3   4 , Anna Walsham  14 , Angela Watts  1 , James Whittaker  15 , Laura Yarnell  3   4 , Anthony Threlfall  3 , Phil V Barber  1 , Janet Tonge  3   4 , Richard Booton  1
Affiliations
Multicenter Study

Second round results from the Manchester 'Lung Health Check' community-based targeted lung cancer screening pilot

Phil A Crosbie et al. Thorax. 2019 Jul.

Abstract

We report results from the second annual screening round (T1) of Manchester's 'Lung Health Check' pilot of community-based lung cancer screening in deprived areas (undertaken June to August 2017). Screening adherence was 90% (n=1194/1323): 92% of CT scans were classified negative, 6% indeterminate and 2.5% positive; there were no interval cancers. Lung cancer incidence was 1.6% (n=19), 79% stage I, treatments included surgery (42%, n=9), stereotactic ablative radiotherapy (26%, n=5) and radical radiotherapy (5%, n=1). False-positive rate was 34.5% (n=10/29), representing 0.8% of T1 participants (n=10/1194). Targeted community-based lung cancer screening promotes high screening adherence and detects high rates of early stage lung cancer.

Keywords: lung cancer.

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Conflict of interest statement

Competing interests: None declared.

Figures

Figure 1
Figure 1
Diagram showing flow of participants through the screening service. LDCT, low-dose CT scan; MDT, multidisciplinary team.
See this image and copyright information in PMC

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