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Review
. 1988:27 Suppl 2:12-8.
doi: 10.1093/rheumatology/xxvii.suppl_2.12.

Molecular biology of the HLA-B27 locus

Free article
Review

Molecular biology of the HLA-B27 locus

E H Weiss et al. Br J Rheumatol. 1988.
Free article

Abstract

The molecular biology of the HLA-B27 locus is reviewed. The HLA-B27 gene itself does not differ between healthy individuals and ankylosing spondylitis patients. Several unique features of the HLA-B27 molecule have been identified and one epitope was proposed to cross-react with bacterial proteins.

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