Molecular biology of the HLA-B27 locus
- PMID: 3042071
- DOI: 10.1093/rheumatology/xxvii.suppl_2.12
Molecular biology of the HLA-B27 locus
Abstract
The molecular biology of the HLA-B27 locus is reviewed. The HLA-B27 gene itself does not differ between healthy individuals and ankylosing spondylitis patients. Several unique features of the HLA-B27 molecule have been identified and one epitope was proposed to cross-react with bacterial proteins.
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