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Review
. 1988 Mar;8(1):19-25.
doi: 10.1007/BF00712907.

Molecular mechanisms of exocytosis: the adrenal chromaffin cell as a model system

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Review

Molecular mechanisms of exocytosis: the adrenal chromaffin cell as a model system

W J Strittmatter. Cell Mol Neurobiol. 1988 Mar.

Abstract

1. The release of neurotransmitters, hormones, and enzymes involves exquisitely regulated events which ultimately result in the fusion of the secretory vesicle with the cell's plasma membrane, releasing the vesicle contents into the extracellular space. 2. The biochemical and cellular mechanisms mediating exocytosis have been extensively studied in a model system of primary cultured adrenal chromaffin cells. 3. This paper briefly reviews current understanding, and directions of future studies in exocytosis using this model system.

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