Molecular mechanisms of exocytosis: the adrenal chromaffin cell as a model system
- PMID: 3042141
- PMCID: PMC11567328
- DOI: 10.1007/BF00712907
Molecular mechanisms of exocytosis: the adrenal chromaffin cell as a model system
Abstract
1. The release of neurotransmitters, hormones, and enzymes involves exquisitely regulated events which ultimately result in the fusion of the secretory vesicle with the cell's plasma membrane, releasing the vesicle contents into the extracellular space. 2. The biochemical and cellular mechanisms mediating exocytosis have been extensively studied in a model system of primary cultured adrenal chromaffin cells. 3. This paper briefly reviews current understanding, and directions of future studies in exocytosis using this model system.
References
-
- Amy, C. M., and Krishner, N. (1981). Phosphorylation of adrenal medulla cell proteins in conjunction with stimulation of catecholamine secretion.J. Neurochem.36847–854. - PubMed
-
- Baker, P. F., and Knight, D. E. (1984). Calcium control of exocytosis in bovine adrenal medullary cells.TINS April:120–126. - PubMed
-
- Boulter, J.,et al. (1986). Isolation of a cDNA clone coding for a possible neural nicotinic acetylcholine receptorα-subunit.Nature319368–374. - PubMed
-
- Burgoyne, R. D. (1984). Mechanisms of secretion from adrenal chromaffin cells.Biochim. Biophys. Acta779201–216. - PubMed
-
- Burgoyne, R. D. (1987). Control of exocytosis.Nature328112–113. - PubMed
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