Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 1988 May;13(5):369-75.
doi: 10.1007/BF00365657.

MAL64c is a global regulator of alpha-glucoside fermentation: identification of a new gene involved in melezitose fermentation

E L Perkins  1 , R B Needleman
Affiliations

MAL64c is a global regulator of alpha-glucoside fermentation: identification of a new gene involved in melezitose fermentation

E L Perkins et al. Curr Genet. 1988 May.

Abstract

Maltase constitutive mutants at the MAL6 locus have been mapped to the newly identified regulatory gene MAL64c. We show here that MAL64c has in addition pleiotropic effects on sugar fermentation: MAL64c strains constitutively synthesize an alpha-methylglucosidase and can complement a new gene, MTP1, for the fermentation of melezitose and alpha-methylglucoside. MTP1, maps near MAL1, and either encodes a permease which transports melezitose, alpha-methylglucoside, and maltose or regulates the activity of such a permease. This work shows that MAL64c, a trans-acting regulatory gene, is a global regulatory gene affecting several different pathways of alpha-glucoside metabolism.

PubMed Disclaimer

Similar articles

See all similar articles

Cited by

References

    1. Genetica. 1953;26(5-6):430-44 - PubMed
    1. Mol Gen Genet. 1985;200(1):1-8 - PubMed
    1. Mol Gen Genet. 1974;131(2):113-21 - PubMed
    1. Biochem Biophys Res Commun. 1967 May 5;27(3):305-8 - PubMed
    1. Proc Natl Acad Sci U S A. 1986 Sep;83(17):6553-7 - PubMed

Publication types

LinkOut - more resources