Epithelioid Sarcoma

Excerpt

Epithelioid sarcoma is a rare and aggressive soft tissue sarcoma characterized by both epithelial and mesenchymal differentiation. This condition most commonly affects young adults and typically presents as a painless and slow-growing mass often located in the distal extremities. Epithelioid sarcoma is locally invasive and frequently metastasizes to regional lymph nodes and distant sites. Diagnosis is determined by tissue biopsy, while imaging studies are essential for assessing the extent of the primary tumor and identifying metastatic disease.

Complete surgical resection is curative in early-stage disease. However, local recurrence and late distant metastases may occur, necessitating long-term surveillance. Radiation therapy may be used as an adjunct treatment and as a palliative measure. Recently, treatment options have evolved with the development of targeted therapies, which aim to improve patient outcomes.