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. 2018 Oct 30;3(6):e000446.
doi: 10.1136/esmoopen-2018-000446. eCollection 2018.

Precision oncology: separating the wheat from the chaff

Jordi Remon  1 , Rodrigo Dienstmann  2
Affiliations

Precision oncology: separating the wheat from the chaff

Jordi Remon et al. ESMO Open. .

Abstract

Precision oncology based on next-generation sequencing (NGS) test is growing in daily clinical practice. However, the real impact of this strategy in patients' outcome on a large scale remains uncertain. In this review, we summarise existing literature on this topic, limitations for broad NGS implementation, bottlenecks in genomic variant interpretation and the role of molecular tumour boards.

Keywords: next-generation sequencing; oncogenic-addicted tumors; personalized medicine.

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Conflict of interest statement

Competing interests: None declared.

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