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. 2018 Nov 8:27:e20180088.
doi: 10.1590/1678-7757-2018-0088.

Correlation of salivary immunoglobulin A with Body Mass Index and fat percentage in overweight/obese children

Mayra Manoella Perez  1 , Juliana Souza Pessoa  1 , Ana Lídia Ciamponi  2 , Michele Baffi Diniz  1 , Maria Teresa Botti Rodrigues Santos  1 , Heloísa Helena de Oliveira Alves  3 , Renata Gorjão  1 , Renata Oliveira Guaré  1
Affiliations

Correlation of salivary immunoglobulin A with Body Mass Index and fat percentage in overweight/obese children

Mayra Manoella Perez et al. J Appl Oral Sci. .

Abstract

Obesity is considered a risk factor for periodontal health due to the low- grade inflammation promoted by the increased adipose tissue.

Objective: This study aimed to determine correlations and associations between gingival inflammation (Simplified Oral Hygiene Index, and Gingival Index), salivary immunoglobulin A (s-IgA), and salivary parameters (salivary flow and osmolality) in normal-weight and overweight/obese children.

Material and methods: Ninety-one children, aged 6 to 12 years old (8.6±1.9 years), were divided into two groups according to their body mass index (BMI), circumferences, skinfold measurements and body fat percentage: normal- weight group (NWG; n =50) and overweight/obese group (OG; n =41). A calibrated examiner performed the clinical examination using the Simplified Oral Hygiene Index, Gingival Index, and salivary collection. Data analysis included descriptive statistics and association tests ( p <0.05).

Results: OG presented statistically higher s-IgA values compared with NWG, especially among the obese children ( p <0.05). Significant positive correlations between s-IgA and salivary osmolality in OG ( p <0.05), and between s-IgA and BMI values ( p <0.05) and body fat percentage ( p <0.05) were observed among all the children. Effect size varied from moderate for s-IgA values ( d =0.57) to large for BMI ( d =2.60).

Conclusion: Gingival inflammation and salivary parameters were similar for NWG and OG; however, s-IgA presented higher values in OG, with correlations between BMI and body fat percentage.

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Figures

Figure 1
Figure 1. Salivary IgA concentrations according to the classification of weight status.
See this image and copyright information in PMC

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