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Review
. 2018 Sep-Oct;23(5):351-361.
doi: 10.5863/1551-6776-23.5.351.

Evolving Pharmacotherapeutic Strategies for Type 1 Diabetes Mellitus

Samie Sabet, Michelle E Condren, Angela F Boston, Lauren C Doak, Laura J Chalmers
Review

Evolving Pharmacotherapeutic Strategies for Type 1 Diabetes Mellitus

Samie Sabet et al. J Pediatr Pharmacol Ther. 2018 Sep-Oct.

Abstract

Despite pharmacotherapeutic advancements in the management of type 1 diabetes mellitus during the past several decades, patients struggle to achieve glycemic goals. Additionally, hypoglycemia, especially in extremes of age, decreases quality of life. The lack of optimal glycemic control and risk for hypoglycemia are multifactorial. Nevertheless, endeavors aiming to develop pharmacotherapeutic options with enhanced pharmacokinetic, pharmacodynamic, and clinical profiles continue. This review article discusses recent ventures in 3 categories of insulin, non-insulin, and glucagon products.

Keywords: diabetes; glucagon; insulin; non-insulin; pediatrics; type 1 diabetes mellitus.

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Conflict of interest statement

Disclosures The authors declare no conflicts or financial interest in any product or service mentioned in the manuscript, including grants, equipment, medications, employment, gifts and honoraria.

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