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. 2019 Feb;40(2):327-332.
doi: 10.1007/s10072-018-3622-9. Epub 2018 Nov 15.

Intrathecal nusinersen treatment for SMA in a dedicated neuromuscular clinic: an example of multidisciplinary and integrated care

Valeria A Sansone  1 , Emilio Albamonte  2 , Francesca Salmin  2 , Jacopo Casiraghi  2 , Alice Pirola  2 , Massimo Bettinelli  2 , Fabrizio Rao  2 , Luca Mancini  3 , Nicola Tovaglieri  3 , Fausto Fedeli  3 , Paolo Stoia  3 , Maurizio Heinen  3 , Valeria Cozzi  3 , Elena Carraro  2 , Christian Lunetta  2 , Alessandra Di Bari  2 , Eugenio Mercuri  4 ; Italian EAP working group
Collaborators, Affiliations

Intrathecal nusinersen treatment for SMA in a dedicated neuromuscular clinic: an example of multidisciplinary and integrated care

Valeria A Sansone et al. Neurol Sci. 2019 Feb.

Abstract

Nusinsersen is now available in Italy for all SMA types. We describe the experience with intrathecal treatment with nusinersen in 50 patients with SMA at the NEMO Center (NEuroMuscular Omniservice Clinical Center) in Milan, a neuromuscular patient-centered clinic hosted within Niguarda Hospital, a National Public General Hospital. Our results indicate that the pathway of care described outweighs the burden due to the repeated intrathecal injections. Irrespective of age and severity, the treatment is feasible, accessible, and replicable provided that there is a multidisciplinary team having experience and training in SMA.

Keywords: Integrated care; Multidisciplinary; Nusinersen; Spinal muscular atrophy; Spinraza.

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