Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Comment
. 2018 Nov 15;379(20):1971-2.
doi: 10.1056/NEJMc1811150.

Procalcitonin-Guided Antibiotic Use

Michael S Pulia  1   2 , Lucas T Schulz  1 , Barry C Fox  1
Affiliations
Comment

Procalcitonin-Guided Antibiotic Use

Michael S Pulia et al. N Engl J Med. .
No abstract available

PubMed Disclaimer

Conflict of interest statement

Disclaimers: No potential conflict of interest relevant to this letter was reported.

Comment in

  • Procalcitonin-Guided Antibiotic Use.
    Huang DT, Yealy DM, Angus DC; the ProACT Investigators. Huang DT, et al. N Engl J Med. 2018 Nov 15;379(20):1973. doi: 10.1056/NEJMc1811150. N Engl J Med. 2018. PMID: 30428287 No abstract available.

Comment on

  • Procalcitonin-Guided Use of Antibiotics for Lower Respiratory Tract Infection.
    Huang DT, Yealy DM, Filbin MR, Brown AM, Chang CH, Doi Y, Donnino MW, Fine J, Fine MJ, Fischer MA, Holst JM, Hou PC, Kellum JA, Khan F, Kurz MC, Lotfipour S, LoVecchio F, Peck-Palmer OM, Pike F, Prunty H, Sherwin RL, Southerland L, Terndrup T, Weissfeld LA, Yabes J, Angus DC; ProACT Investigators. Huang DT, et al. N Engl J Med. 2018 Jul 19;379(3):236-249. doi: 10.1056/NEJMoa1802670. Epub 2018 May 20. N Engl J Med. 2018. PMID: 29781385 Free PMC article. Clinical Trial.

References

    1. Huang DT, Yealy DM, Filbin MR, Brown AM, Chang C‐ CH, Doi Y, Donnino MW, Fine J, Fine MJ, Fischer MA, Holst JM, Hou PC, Kellum JA, Khan F, Kurz MC, Lotfipour S, LoVecchio F, Peck‐Palmer OM, Pike F, Prunty H, Sherwin RL, Southerland L, Terndrup T, Weissfeld LA, Yabes J, Angus DC. Procalcitonin‐Guided Use of Antibiotics for Lower Respiratory Tract Infection. N Engl J Med. 2018;0(0):null. doi:10.1056/NEJMoa1802670. - DOI - PMC - PubMed
    1. Schuetz P, Wirz Y, Sager R, Christ‐Crain M, Stolz D, Tamm M, Bouadma L, Luyt CE, Wolff M, Chastre J, Tubach F, Kristoffersen KB, Burkhardt O, Welte T, Schroeder S, Nobre V, Wei L, Bucher HC, Bhatnagar N, Annane D, Reinhart K, Branche A, Damas P, Nijsten M, de Lange DW, Deliberato RO, Lima SS, Maravić‐Stojković V, Verduri A, Cao B, Shehabi Y, Beishuizen A, Jensen J‐ US, Corti C, Van Oers JA, Falsey AR, de Jong E, Oliveira CF, Beghe B, Briel M, Mueller B. Procalcitonin to initiate or discontinue antibiotics in acute respiratory tract infections. Cochrane Database Syst Rev. 2017;10:CD007498. doi:10.1002/14651858.CD007498.pub3. - DOI - PMC - PubMed
    1. Simon L, Gauvin F, Amre DK, Saint‐Louis P, Lacroix J. Serum Procalcitonin and C‐Reactive Protein Levels as Markers of Bacterial Infection: A Systematic Review and Meta‐analysis. Clin Infect Dis. 2004;39(2):206–217. doi:10.1086/421997. - DOI - PubMed
    1. Sikka R, Tommaso LH, Kaucky C, Kulstad EB. Diagnosis of pneumonia in the ED has poor accuracy despite diagnostic uncertainty. Am J Emerg Med. 2012;30(6):881–885. doi:10.1016/j.ajem.2011.06.006. - DOI - PubMed
    1. Jain S, Self WH, Wunderink RG, Fakhran S, Balk R, Bramley AM, Reed C, Grijalva CG, Anderson EJ, Courtney DM, Chappell JD, Qi C, Hart EM, Carroll F, Trabue C, Donnelly HK, Williams DJ, Zhu Y, Arnold SR, Ampofo K, Waterer GW, Levine M, Lindstrom S, Winchell JM, Katz JM, Erdman D, Schneider E, Hicks LA, McCullers JA, Pavia AT, Edwards KM, Finelli L. Community‐Acquired Pneumonia Requiring Hospitalization among U.S. Adults. N Engl J Med. 2015;373(5):415–427. doi:10.1056/NEJMoa1500245. - DOI - PMC - PubMed