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Comment
. 2018 Nov 14;24(5):616-618.
doi: 10.1016/j.chom.2018.10.013.

MDVs: Spare the SOD and Spoil the Bug

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MDVs: Spare the SOD and Spoil the Bug

Syed Saad Hussain et al. Cell Host Microbe. .
Free article

Abstract

Mitochondrial reactive oxygen species are important anti-microbial weapons utilized by phagocytes of the innate immune system. In this issue of Cell Host and Microbe, Abuaita et al. (2018) show that in macrophages, mitochondrial-derived vesicles deliver the superoxide dismutase Sod2 to bacteria-containing phagosomes to produce hydrogen peroxide and kill invading bacteria.

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