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doi: 10.1016/j.chom.2018.10.017.
Hepatitis C Virus Neutralizing Antibodies: Is a Vaccine Still Possible?
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- PMID: 30439338
- DOI: 10.1016/j.chom.2018.10.017
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Hepatitis C Virus Neutralizing Antibodies: Is a Vaccine Still Possible?
Cell Host Microbe.
.
Free article
Abstract
Many hurdles have plagued the development of an effective vaccine for hepatitis C virus. In this issue of Cell Host & Microbe, Kinchen et al. (2018) and Flyak et al. (2018) report on the characterization of neutralizing antibodies from individuals that spontaneously cleared infection, providing insights that promise to propel vaccine design forward.
Copyright © 2018 Elsevier Inc. All rights reserved.
Comment on
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HCV Broadly Neutralizing Antibodies Use a CDRH3 Disulfide Motif to Recognize an E2 Glycoprotein Site that Can Be Targeted for Vaccine Design.Cell Host Microbe. 2018 Nov 14;24(5):703-716.e3. doi: 10.1016/j.chom.2018.10.009. Cell Host Microbe. 2018. PMID: 30439340 Free PMC article.
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Broadly Neutralizing Antibody Mediated Clearance of Human Hepatitis C Virus Infection.Cell Host Microbe. 2018 Nov 14;24(5):717-730.e5. doi: 10.1016/j.chom.2018.10.012. Cell Host Microbe. 2018. PMID: 30439341 Free PMC article.
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