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Comparative Study
. 2019 May;46(5):455-459.
doi: 10.3899/jrheum.180176. Epub 2018 Nov 15.

Fertility and Ovarian Reserve among Women with Rheumatoid Arthritis

Amanda M Eudy  1   2 , Gary McDaniel  3   4 , William W Hurd  3   4 , Megan E B Clowse  3   4
Affiliations
Comparative Study

Fertility and Ovarian Reserve among Women with Rheumatoid Arthritis

Amanda M Eudy et al. J Rheumatol. 2019 May.

Abstract

Objective: We sought to identify causes for infertility in women with and without rheumatoid arthritis (RA).

Methods: Women with RA were matched to healthy controls. Differences in anti-Müllerian hormone (AMH) and anovulation were analyzed.

Results: Women with RA had lower AMH (β -1.05, 95% CI -2.09 to -0.005), but no difference was observed when AMH was log-transformed. No difference in anovulation was observed. Infertility prevalence was similar between groups, primarily attributable to polycystic ovary syndrome in healthy controls but largely unexplained in women with RA.

Conclusion: AMH was lower in women with RA, but reasons for infertility among women with RA remain unknown.

Keywords: ANTI–MÜLLERIAN HORMONE; FERTILITY; PROGESTERONE; RHEUMATOID ARTHRITIS.

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