Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2018 Sep 11;10(9):e3284.
doi: 10.7759/cureus.3284.

The Prevention and Management of Contrast-induced Acute Kidney Injury: A Mini-review of the Literature

Affiliations
Review

The Prevention and Management of Contrast-induced Acute Kidney Injury: A Mini-review of the Literature

Asad Ali et al. Cureus. .

Abstract

Contrast-induced acute kidney injury, also called contrast-induced nephropathy, is one of the main causes of acute renal failure/acute kidney injury (AKI) in hospitalized patients within 48 to 72 hours of contrast media administration during various radiologic procedures. Several factors can be responsible for contrast-induced acute tubular necrosis (ATN); however, patient and procedure-related factors play the lead role in determining the development of contrast-induced nephropathy. There is no definitive treatment and hydration remains the mainstay preventive strategy. This article will review the incidence, criteria for definitive diagnosis, and an effective approach on how to prevent contrast-induced nephropathy in a clinical setup.

Keywords: acute kidney injury; acute tubular necrosis; contrast induced nephropathy; hemodialysis; nephropathy; nephroprotective; nephrotoxicity; pharmacologic treatment; radiological; volume expansion.

PubMed Disclaimer

Conflict of interest statement

The authors have declared that no competing interests exist.

References

    1. Iodinated contrast media and their adverse reactions. Singh J, Daftary A. J Nucl Med Technol. 2008;36:69–74. - PubMed
    1. Contrast-induced nephropathy: from pathophysiology to preventive strategies. Azzalini L, Spagnoli V, Ly HQ. Can J Cardiol. 2016;32:247–255. - PubMed
    1. Contrast-induced nephropathy. Mohammed NMA, Mahfouz A, Achkar K, Rafie IM, Hajar R. Heart Views. 2013;14:106–116. - PMC - PubMed
    1. Contrast-induced nephropathy: a clinical and evidence-based approach. Tepel M, Aspelin P, Lameire N. https://www.ncbi.nlm.nih.gov/pubmed/16606801. Circulation. 2006;113:1799–1806. - PubMed
    1. Delayed adverse reaction to contrast-enhanced CT: a prospective single-center study comparison to control group without enhancement. Loh S, Bagheri S, Katzberg RW, Fung MA, Li CS. Radiology. 2010;255:764–771. - PMC - PubMed

LinkOut - more resources