The Prevention and Management of Contrast-induced Acute Kidney Injury: A Mini-review of the Literature
- PMID: 30443454
- PMCID: PMC6235634
- DOI: 10.7759/cureus.3284
The Prevention and Management of Contrast-induced Acute Kidney Injury: A Mini-review of the Literature
Abstract
Contrast-induced acute kidney injury, also called contrast-induced nephropathy, is one of the main causes of acute renal failure/acute kidney injury (AKI) in hospitalized patients within 48 to 72 hours of contrast media administration during various radiologic procedures. Several factors can be responsible for contrast-induced acute tubular necrosis (ATN); however, patient and procedure-related factors play the lead role in determining the development of contrast-induced nephropathy. There is no definitive treatment and hydration remains the mainstay preventive strategy. This article will review the incidence, criteria for definitive diagnosis, and an effective approach on how to prevent contrast-induced nephropathy in a clinical setup.
Keywords: acute kidney injury; acute tubular necrosis; contrast induced nephropathy; hemodialysis; nephropathy; nephroprotective; nephrotoxicity; pharmacologic treatment; radiological; volume expansion.
Conflict of interest statement
The authors have declared that no competing interests exist.
References
-
- Iodinated contrast media and their adverse reactions. Singh J, Daftary A. J Nucl Med Technol. 2008;36:69–74. - PubMed
-
- Contrast-induced nephropathy: from pathophysiology to preventive strategies. Azzalini L, Spagnoli V, Ly HQ. Can J Cardiol. 2016;32:247–255. - PubMed
-
- Contrast-induced nephropathy: a clinical and evidence-based approach. Tepel M, Aspelin P, Lameire N. https://www.ncbi.nlm.nih.gov/pubmed/16606801. Circulation. 2006;113:1799–1806. - PubMed
Publication types
LinkOut - more resources
Full Text Sources