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Case Reports
. 2018 Aug 15;2(4):304-308.
doi: 10.5811/cpcem.2018.7.38344. eCollection 2018 Nov.

Acute Hepatitis B with Pancreatitis and Cholecystitis Leading to Acute Liver Failure and Death

Andrew R Albert  1 , Ronald Valencia  2 , Janet A Smereck  2
Affiliations
Case Reports

Acute Hepatitis B with Pancreatitis and Cholecystitis Leading to Acute Liver Failure and Death

Andrew R Albert et al. Clin Pract Cases Emerg Med. .

Abstract

Acute liver failure is defined as severe acute liver injury, concurrent with encephalopathy and loss of hepatic synthetic function, in a patient without known pre-existing liver disease. Evaluation of acute liver failure in the emergency department should focus on identification of treatable causes. Acute liver failure from acute hepatitis B infection is a rare but potentially lethal occurrence. Multi-organ dysfunction from acute liver failure may be exacerbated by metabolic and inflammatory reactions associated with acute pancreatitis, which accompanies approximately 5% of cases of acute viral hepatitis. Transplant-free survival rate with liver failure from acute hepatitis B is unfortunately less than 20%.

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Conflict of interest statement

Conflicts of Interest: By the CPC-EM article submission agreement, all authors are required to disclose all affiliations, funding sources and financial or management relationships that could be perceived as potential sources of bias. The authors disclosed none.

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