Re-viewing the 3D Organization of mRNPs
- PMID: 30444995
- DOI: 10.1016/j.molcel.2018.10.044
Re-viewing the 3D Organization of mRNPs
Abstract
In this issue of Molecular Cell, using leading-edge technologies, Metkar et al. (2018) and Adivarahan et al. (2018) revisit the spatial organization of mRNPs, showing that they form flexible rod-like structures prior to translation that decompact during translation while the closed-loop conformation is rarely observed.
Copyright © 2018 Elsevier Inc. All rights reserved.
Comment on
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Spatial Organization of Single mRNPs at Different Stages of the Gene Expression Pathway.Mol Cell. 2018 Nov 15;72(4):727-738.e5. doi: 10.1016/j.molcel.2018.10.010. Epub 2018 Nov 8. Mol Cell. 2018. PMID: 30415950 Free PMC article.
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Higher-Order Organization Principles of Pre-translational mRNPs.Mol Cell. 2018 Nov 15;72(4):715-726.e3. doi: 10.1016/j.molcel.2018.09.012. Epub 2018 Nov 8. Mol Cell. 2018. PMID: 30415953 Free PMC article.