Flaviviruses Hit a Moving Target
- PMID: 30445035
- PMCID: PMC8386920
- DOI: 10.1016/j.cell.2018.10.060
Flaviviruses Hit a Moving Target
Abstract
The enteric nervous system (ENS) is central to intestinal motility and a candidate target for the heterogeneous spectrum of dysmotility diseases. White et al. reveal that relapsing intestinal dysmotility occurs when partial ENS depletion by enteric neurotropic viruses is followed by functional impairment due to intermittent nonspecific intestinal inflammation.
Copyright © 2018 Elsevier Inc. All rights reserved.
Conflict of interest statement
DECLARATION OF INTERESTS
J.B. declares scientific advisory board member roles for Janssen, Allergan, Pro-lacta Bioscience, and UBiome.
Figures
Comment on
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Intestinal Dysmotility Syndromes following Systemic Infection by Flaviviruses.Cell. 2018 Nov 15;175(5):1198-1212.e12. doi: 10.1016/j.cell.2018.08.069. Epub 2018 Oct 4. Cell. 2018. PMID: 30293866 Free PMC article.
References
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- Furness JB (2012). The enteric nervous system and neurogastroenterology. Nat. Rev. Gastroenterol. Hepatol 9, 286–294. - PubMed
