Challenges in Implementing Treat-to-Target Strategies in Rheumatology

doi:10.1016/j.rdc.2018.09.007

Review

. 2019 Feb;45(1):101-112.

doi: 10.1016/j.rdc.2018.09.007.

Challenges in Implementing Treat-to-Target Strategies in Rheumatology

Julia A Ford¹, Daniel H Solomon²

Affiliations

¹ Division of Rheumatology, Brigham and Women's Hospital, 60 Fenwood Road, Boston, MA 02115, USA. Electronic address: jrford@partners.org.
² Division of Rheumatology, Brigham and Women's Hospital, 60 Fenwood Road, Boston, MA 02115, USA; Division of Pharmacoepidemiology, Brigham and Women's Hospital, 60 Fenwood Road, Boston, MA 02115, USA.

PMID: 30447739
PMCID: PMC8491430
DOI: 10.1016/j.rdc.2018.09.007

Review

Challenges in Implementing Treat-to-Target Strategies in Rheumatology

Julia A Ford et al. Rheum Dis Clin North Am. 2019 Feb.

. 2019 Feb;45(1):101-112.

doi: 10.1016/j.rdc.2018.09.007.

Authors

Julia A Ford¹, Daniel H Solomon²

Affiliations

¹ Division of Rheumatology, Brigham and Women's Hospital, 60 Fenwood Road, Boston, MA 02115, USA. Electronic address: jrford@partners.org.
² Division of Rheumatology, Brigham and Women's Hospital, 60 Fenwood Road, Boston, MA 02115, USA; Division of Pharmacoepidemiology, Brigham and Women's Hospital, 60 Fenwood Road, Boston, MA 02115, USA.

PMID: 30447739
PMCID: PMC8491430
DOI: 10.1016/j.rdc.2018.09.007

Abstract

Despite evidence that treat-to-target (TTT) approaches lead to better disease outcomes in RA, TTT is not widely implemented in rheumatology clinics in North America. This article discusses the barriers (including access to care, patient and physician factors, and systems issues) to implementing TTT in the clinic, and proposes possible solutions and future research directions.

Keywords: Rheumatoid arthritis (RA); Treat-to-target; Treatment strategy.

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References

1. Solomon DH, Bitton A, Katz JN, Radner H, Brown EM, Fraenkel L. Review: Treat to Target in Rheumatoid Arthritis: Fact, Fiction, or Hypothesis? Arthritis Rheumatol. 2014;66(4):775–782. doi:10.1002/art.38323 - DOI - PMC - PubMed
1. Smolen JS, Aletaha D, Bijlsma JWJ, et al.Treating rheumatoid arthritis to target: recommendations of an international task force. Ann Rheum Dis. 2010;69(4):631–637. doi:10.1136/ard.2009.123919 - DOI - PMC - PubMed
1. Smolen JS, Breedveld FC, Burmester GR, et al.Treating rheumatoid arthritis to target: 2014 update of the recommendations of an international task force. Ann Rheum Dis. 2016;75(1):3–15. doi:10.1136/annrheumdis-2015-207524 - DOI - PMC - PubMed
1. Singh JA, Furst DE, Bharat A, et al.2012 Update of the 2008 American College of Rheumatology recommendations for the use of disease-modifying antirheumatic drugs and biologic agents in the treatment of rheumatoid arthritis. Arthritis Care Res (Hoboken). 2012;64(5):625–639. doi:10.1002/acr.21641 - DOI - PMC - PubMed
1. Smolen JS, Landewé R, Breedveld FC, et al.EULAR recommendations for the management of rheumatoid arthritis with synthetic and biological disease-modifying antirheumatic drugs: 2013 update. Ann Rheum Dis. 2014;73(3):492–509. doi:10.1136/annrheumdis-2013-204573 - DOI - PMC - PubMed

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[1] Solomon DH, Bitton A, Katz JN, Radner H, Brown EM, Fraenkel L. Review: Treat to Target in Rheumatoid Arthritis: Fact, Fiction, or Hypothesis? Arthritis Rheumatol. 2014;66(4):775–782. doi:10.1002/art.38323 - DOI - PMC - PubMed

[2] Solomon DH, Bitton A, Katz JN, Radner H, Brown EM, Fraenkel L. Review: Treat to Target in Rheumatoid Arthritis: Fact, Fiction, or Hypothesis? Arthritis Rheumatol. 2014;66(4):775–782. doi:10.1002/art.38323 - DOI - PMC - PubMed

[3] Smolen JS, Aletaha D, Bijlsma JWJ, et al.Treating rheumatoid arthritis to target: recommendations of an international task force. Ann Rheum Dis. 2010;69(4):631–637. doi:10.1136/ard.2009.123919 - DOI - PMC - PubMed

[4] Smolen JS, Aletaha D, Bijlsma JWJ, et al.Treating rheumatoid arthritis to target: recommendations of an international task force. Ann Rheum Dis. 2010;69(4):631–637. doi:10.1136/ard.2009.123919 - DOI - PMC - PubMed

[5] Smolen JS, Breedveld FC, Burmester GR, et al.Treating rheumatoid arthritis to target: 2014 update of the recommendations of an international task force. Ann Rheum Dis. 2016;75(1):3–15. doi:10.1136/annrheumdis-2015-207524 - DOI - PMC - PubMed

[6] Smolen JS, Breedveld FC, Burmester GR, et al.Treating rheumatoid arthritis to target: 2014 update of the recommendations of an international task force. Ann Rheum Dis. 2016;75(1):3–15. doi:10.1136/annrheumdis-2015-207524 - DOI - PMC - PubMed

[7] Singh JA, Furst DE, Bharat A, et al.2012 Update of the 2008 American College of Rheumatology recommendations for the use of disease-modifying antirheumatic drugs and biologic agents in the treatment of rheumatoid arthritis. Arthritis Care Res (Hoboken). 2012;64(5):625–639. doi:10.1002/acr.21641 - DOI - PMC - PubMed

[8] Singh JA, Furst DE, Bharat A, et al.2012 Update of the 2008 American College of Rheumatology recommendations for the use of disease-modifying antirheumatic drugs and biologic agents in the treatment of rheumatoid arthritis. Arthritis Care Res (Hoboken). 2012;64(5):625–639. doi:10.1002/acr.21641 - DOI - PMC - PubMed

[9] Smolen JS, Landewé R, Breedveld FC, et al.EULAR recommendations for the management of rheumatoid arthritis with synthetic and biological disease-modifying antirheumatic drugs: 2013 update. Ann Rheum Dis. 2014;73(3):492–509. doi:10.1136/annrheumdis-2013-204573 - DOI - PMC - PubMed

[10] Smolen JS, Landewé R, Breedveld FC, et al.EULAR recommendations for the management of rheumatoid arthritis with synthetic and biological disease-modifying antirheumatic drugs: 2013 update. Ann Rheum Dis. 2014;73(3):492–509. doi:10.1136/annrheumdis-2013-204573 - DOI - PMC - PubMed

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Challenges in Implementing Treat-to-Target Strategies in Rheumatology

Affiliations

Challenges in Implementing Treat-to-Target Strategies in Rheumatology

Authors

Affiliations

Abstract

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References

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Grants and funding

LinkOut - more resources

Full Text Sources

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Medical